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Cover figure depicts statistical 3-dimensional maps showing local differences in hippocampal anatomy between unmedicated bipolar patients vs lithium-treated bipolar patients. Figure is courtesy of Drs CE Bearden and PM Thompson of the Semel Institute for Neuroscience and Human Behavior and the Laboratory of Neuroimaging, respectively, at University of California, Los Angeles, and Dr JC Soares of the Department of Psychiatry, UNC Chapel Hill School of Medicine.