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Electrochemical carbon dioxide (CO2) reduction in acid with a nano-structured tandem catalyst achieves high single-pass conversion efficiency and selectivity to useful C–C coupled products, bringing the process closer to commercial viability.
Conserved regions of the circular DNA sequence of the M13mp18 bacteriophage, which is used as a scaffold for DNA origami construction, are targeted with specific hybridization-chain-reaction probes. The probes enable sensitive detection of DNA origami nanostructures in cells, organoids and tissues to assess their biodistribution and stability.
A biohybrid, leaf-spring design of DNA origami functions as a pulsating nanoengine that exploits the DNA-templated RNA transcription mechanism while consuming nucleoside triphosphates as fuel. The nanoengine also drives a nanomechanical follower structure.
Directionality of nonlinear emission from a dielectric metasurface is controlled by fine-tuning the relative time delay and polarization of two pulsed pump beams.
To determine the physiologically relevant oligomeric form of membrane proteins is extremely challenging. Now an elegant method of counting the oligomers in membrane proteins in near-native states is presented, using photobleaching and nanodiscs formed directly from cellular membranes.
In a major advancement for synthetic biology, dynamin A has been identified as a minimal component enabling cell division in synthetic cells, moving us one step nearer to realizing the ambition of creating synthetic life forms.
DNA-origami nanostructures self-assembled at milder physicochemical parameters in magnesium-free conditions achieve structural complexities akin to those formed by thermal annealing at elevated temperatures, and open a route to assembling DNA nanomachines in physiological conditions.
By integrating a 3D nanopositioner with a solid-state nanopore and surface-tethered molecules, precise spatiotemporal control over single DNA strands is achieved, enabling numerous re-reads and raising the signal-to-noise ratio far beyond previous solid-state nanopore methods.