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Editorial

Of mice and men p395

doi:10.1038/nnano.2009.162

We need a systematic way to formulate and tackle problems in nanotoxicology, and to compare and combine the results from individual studies.

Subject Categories: Nanomedicine | Environmental, health and safety issues


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Thesis

Plenty of gloom and doom at the bottom? pp396 - 397

Chris Toumey

doi:10.1038/nnano.2009.163

The relationship between humans and technology is often viewed as a debate between technophobes who oppose technology, irrespective of its benefits, and technophiles who think that all technology is good. Chris Toumey prefers the cyborg point of view.

Subject Category: Ethical, legal and other societal issues


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Feature

Strictly nanotubes in Beijing pp398 - 399

Adarsh Sandhu

doi:10.1038/nnano.2009.164

A collaboration between China's leading university and one of the world's biggest industrial companies is bringing a range of nanotube-based materials and devices to the market.

Subject Categories: Education and research | Industry and IPR


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Research Highlights

Our choice from the recent literature pp400 - 401

doi:10.1038/nnano.2009.165


Top down bottom up: Strength in numbers p401

doi:10.1038/nnano.2009.166

Computational screening has turned up a fullerene derivative that might help fight the HIV virus.


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News and Views

Nanobiotechnology: A fluid approach to simple circuits pp403 - 404

Vicente M. Aguilella & Antonio Alcaraz

doi:10.1038/nnano.2009.168

Using simple components such as oil, salt water, lipids and proteins, plus routine genetic engineering techniques, it is possible to create simple nanofluidic circuits.

Subject Category: Nanobiotechnology


Nanoelectromechanical systems: Mass spec goes nanomechanical pp404 - 405

Anja Boisen

doi:10.1038/nnano.2009.169

A new approach to mass spectrometry based on nanoelectromechanical systems removes the need to ionize molecules before their mass can be determined.

Subject Categories: Nanobiotechnology | Nanometrology and instrumentation | Nanosensors and other devices | NEMS


Ferroelectric memory: Slim fast p405

Michael Segal

doi:10.1038/nnano.2009.161

Subject Categories: Electronic properties and devices | Surface patterning and imaging


Correlated electron systems: Better than average pp406 - 407

Douglas Natelson

doi:10.1038/nnano.2009.124

Experiments on single-crystal nanobeams have revealed several new aspects of a phenomenon that has puzzled physicists for decades — the metal–insulator transition in vanadium dioxide.

Subject Categories: Electronic properties and devices | NEMS | Structural properties


Nanomaterials: Sticky but not messy pp407 - 408

Zhong Lin Wang

doi:10.1038/nnano.2009.135

Inspired by the feet of the gecko lizard, researchers have tweaked a conventional plasma etching chamber so that it can make reusable adhesives that could have applications in the semiconductor industry.

Subject Categories: Nanomaterials | Synthesis and processing


Nanotoxicology: How do nanotubes suppress T cells? pp409 - 410

Alison Elder

doi:10.1038/nnano.2009.167

Mice inhaling low levels of multiwalled carbon nanotubes show suppressed immune function. New studies suggest that this suppression originates from signals in the lungs.

Subject Categories: Nanomedicine | Environmental, health and safety issues


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Progress Article

Evaluation of nanoparticle immunotoxicity pp411 - 414

Marina A. Dobrovolskaia, Dori R. Germolec & James L. Weaver

doi:10.1038/nnano.2009.175

Subject Categories: Nanomedicine | Environmental, health and safety issues


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Letters

Nanoscale shape-memory alloys for ultrahigh mechanical damping pp415 - 419

Jose San Juan, Maria L. Nó & Christopher A. Schuh

doi:10.1038/nnano.2009.142

Shape-memory alloys undergo reversible transformations between two distinct phases. Now researchers have shown that nanoscale pillars made of shape-memory alloys have a figure of merit for mechanical damping — substantially higher than the figures previously reported for bulk materials — making these nanopillars attractive for use in future microscale and smaller devices.

Subject Categories: Nanomaterials | NEMS | Structural properties


New aspects of the metal–insulator transition in single-domain vanadium dioxide nanobeams pp420 - 424

Jiang Wei, Zenghui Wang, Wei Chen & David H. Cobden

doi:10.1038/nnano.2009.141

Many strongly correlated electron systems have a domain structure that obscures the fundamental properties of the homogeneous material. Experiments on single-domain nanobeams made of vanadium dioxide have revealed several new aspects of the metal–insulator transition in this material.

Subject Categories: Electronic properties and devices | NEMS | Structural properties

See also: News and Views by Natelson


Observation of the triplet exciton in EuS-coated single-walled nanotubes pp425 - 429

Aditya D. Mohite, Tiffany S. Santos, Jagadeesh S. Moodera & Bruce W. Alphenaar

doi:10.1038/nnano.2009.122

Excitons are created when a carbon nanotube absorbs photons. However, the triplet exciton is usually optically inactive, preventing its direct observation, lowering photocurrent efficiency and making optical injection of spin-polarized carriers impossible. Optical excitation of the triplet exciton has now been achieved.

Subject Categories: Carbon nanotubes and fullerenes | Nanomagnetism and spintronics


Multifunctional nanoarchitectures from DNA-based ABC monomers pp430 - 436

Jong B. Lee, Young H. Roh, Soong Ho Um, Hisakage Funabashi, Wenlong Cheng, Judy J. Cha, Pichamon Kiatwuthinon, David A. Muller & Dan Luo

doi:10.1038/nnano.2009.93

Multifunctional nanostructures have been created from DNA-based anisotropic, branched and crosslinkable building blocks — ABC monomers. Using these monomers, a target-driven polymerization process is demonstrated where polymers are generated only in the presence of a specific DNA molecule, leading to highly sensitive pathogen detection. The nanoarchitectures can also be used to deliver drugs to cells.

Subject Categories: Nanobiotechnology | Nanomaterials


Droplet networks with incorporated protein diodes show collective properties pp437 - 440

Giovanni Maglia, Andrew J. Heron, William L. Hwang, Matthew A. Holden, Ellina Mikhailova, Qiuhong Li, Stephen Cheley & Hagan Bayley

doi:10.1038/nnano.2009.121

Aqueous droplets connected by single lipid bilayers have been used to examine the properties of protein channels and pores, and networks of droplets can form microscale batteries and detect light. Now, by inserting an engineered pore with diode-like properties into the interface bilayers, droplet networks that mimic simple electronic devices have been produced.

Subject Categories: Electronic properties and devices | Nanobiotechnology

See also: News and Views by Aguilella & Alcaraz


Transfer of gold nanoparticles from the water column to the estuarine food web pp441 - 444

John L. Ferry, Preston Craig, Cole Hexel, Patrick Sisco, Rebecca Frey, Paul L. Pennington, Michael H. Fulton, I. Geoff Scott, Alan W. Decho, Shosaku Kashiwada, Catherine J. Murphy & Timothy J. Shaw

doi:10.1038/nnano.2009.157

Gold nanorods added to a laboratory-constructed estuarine mesocosm can accumulate in sediments, biofilms and various organisms such as fish, snails and shrimp. Most of the nanorods ended up in biofilms and clams, indicating that these nanoparticles could readily pass from the water column into the marine food web.

Subject Category: Environmental, health and safety issues


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Articles

Towards single-molecule nanomechanical mass spectrometry pp445 - 450

A. K. Naik, M. S. Hanay, W. K. Hiebert, X. L. Feng & M. L. Roukes

doi:10.1038/nnano.2009.152

Mass detection of single biological molecules in real time by a nanoelectromechanical system (NEMS) is demonstrated for the first time, and this is used to perform first generation NEMS-based mass spectrometry. Precipitous frequency shifts, proportional to the mass of the molecules, are recorded in real time by the NEMS mass spectrometry system as protein molecules and nanoparticles adsorb, one-by-one, onto an ultrahigh frequency NEMS resonator.

Subject Categories: Nanobiotechnology | Nanometrology and instrumentation | Nanosensors and other devices | NEMS

See also: News and Views by Boisen


Mechanisms for how inhaled multiwalled carbon nanotubes suppress systemic immune function in mice pp451 - 456

L. A. Mitchell, F. T. Lauer, S. W. Burchiel & J. D. McDonald

doi:10.1038/nnano.2009.151

It has been shown that inhaling multiwalled carbon nanotubes does not lead to significant lung inflammation, but can suppress the immune function of mice. Now it is demonstrated that signals in the lung can activate signals in the spleen to inhibit the immune function of mice inhaling low levels of nanotubes.

Subject Categories: Nanomedicine | Environmental, health and safety issues

See also: News and Views by Elder


Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent pp457 - 463

Lihong Liu, Kaijin Xu, Huaying Wang, P. K. Jeremy Tan, Weimin Fan, Subbu S. Venkatraman, Lanjuan Li & Yi-Yan Yang

doi:10.1038/nnano.2009.153

A class of core–shell nanoparticles self-assembled from amphiphilic peptides can kill a range of bacteria, yeast and fungus. They are more potent than their unassembled peptide counterparts and can suppress bacterial growth in the brains of rabbits infected with meningitis. These particles, which carry a high number of positive charges, are promising antimicrobial agents.

Subject Categories: Molecular self-assembly | Nanomedicine | Nanoparticles


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