Browse Articles

Filter By:

  • Here the authors present a non-FRET DNA-templated silver nanocluster probe that exhibits a distinct colour switch from green to red upon nuclease digestion, visible under UV excitation, offering a low-cost, effective alternative to fluorescent reporters for detecting nuclease activities.

    • Soonwoo Hong
    • Jada N. Walker
    • Hsin-Chih Yeh
    Article
  • Distinguishing proteoforms and post-translational modifications has remained a challenge. Here the authors explore single-molecule fluorescence resonance energy transfer to probe amino acids via DNA exchange and map the location of individual amino acids and post-translational modifications within single full-length protein molecules.

    • Mike Filius
    • Raman van Wee
    • Chirlmin Joo
    Article
  • Scientists encounter pressure to validate their research work, leading to varied benchmarks and methods for performance assessment in the broad energy research field. Interlaboratory studies help highlight discrepancies in reported figures of merit, underscoring the need for standardized protocols, transparent reporting, and detailed analysis for fair comparisons. Here, we discuss this topic, focusing on battery materials.

    • Nella M. Vargas-Barbosa
    Comment
  • An encodable DNA clutch with the ability to recognize microenvironmental molecular inputs intelligently complements the remote control of a 200-nm sized magnetic nanomachine. This nanomachine interacts with biological machinery in vitro when the encoded clutch selectively engages the engine with the rotor while external magnetic fields power the rotation.

    Research Briefing
  • A robust initialization protocol has been demonstrated for a four-qubit nuclear spin register in silicon. The protocol, driven electrically through electric-dipole spin resonance, enables high-fidelity qubit control and hence a route to a register-based quantum computer that exploits the exceptional coherence properties of atom qubits in silicon.

    Research Briefing
  • An electric dipole spin resonance protocol making use of hyperfine interaction enacts high-fidelity initialization of a four-qubit nuclear spin register in silicon. This protocol allows for high-fidelity qubit control and a path towards a register-based quantum computer using the exceptional coherence properties of donors in silicon.

    • J. Reiner
    • Y. Chung
    • M. Y. Simmons
    ArticleOpen Access
  • The nanospace confinement of a magnetic nanoparticle within a porous cage, coupled with an encodable DNA clutch interface, enables a remotely powered and controlled rotary nanomotor that is autoresponsive to its microenvironment.

    • Mouhong Lin
    • Jung-uk Lee
    • Jinwoo Cheon
    Article
  • An intelligent meta-imager can perform multi-channel convolutions to accelerate machine vision for incoherent light.

    • Zheng Huang
    • Hongwei Chen
    News & Views
  • The legal definition of a nanomaterial differs around the world, meaning that the same material may be classified as a nanomaterial, or not, depending on the country where it is classified. The first steps towards converging on an international definition are to recognize the differences between existing nanomaterial definitions and to agree on particle counting methods. Meanwhile, we propose a naming convention that indicates the key criteria of a specific definition of a nanomaterial.

    • Kirsten Rasmussen
    • Juan Riego Sintes
    • Hubert Rauscher
    Comment
  • Ptychography is a coherent diffractive imaging method that enables atomic resolution in four-dimensional scanning transmission electron microscopy. Taking advantage of the nature of the investigated object, and therefore using atomic-orbital-like functions for the reconstruction of the object, the resolution can be further improved to an information limit of 14 pm.

    • Wenfeng Yang
    • Haozhi Sha
    • Rong Yu
    Article
  • Insects have been shown to have the ability to detect different chemical agents. Here, the authors present a nanomaterial-assisted neuromodulation strategy to augment the chemosensory abilities of insects via photothermal effect and on-demand neurotransmitter release from cargo-loaded nanovehicles to augment natural sensory function.

    • Prashant Gupta
    • Rishabh Chandak
    • Srikanth Singamaneni
    Article
  • In vivo positron emission particle tracking (PEPT) remains a challenge due to the lack of single-particle tracers. Here a sub-micrometre silica particle has been radiolabelled and isolated with high specific activity, allowing the dynamic tracing of a single particle in vivo using PEPT in mice.

    • Juan Pellico
    • Laurence Vass
    • Rafael T. M. de Rosales
    ArticleOpen Access
  • Resolving interactions of negligibly charged or neutral small molecules with their binding partners in a label-free manner is challenging. Here the authors present a single-molecule carbon-nanotube biosensor device for capturing aptamer–neurotransmitter kinetics at high temporal resolution, uncovering four-state structural transitions.

    • Yoonhee Lee
    • Jakob Buchheim
    • Kenneth L. Shepard
    Article