A combination of chromosome conformation capture carbon copy (5C), modeling and automated imaging renders an empirical three-dimensional model of a bacterial genome.
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References
Umbarger, M.A. et al. The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation. Mol. Cell 44, 252–264 (2011).
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Rusk, N. Three-dimensional genetics. Nat Methods 9, 14–15 (2012). https://doi.org/10.1038/nmeth.1843
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DOI: https://doi.org/10.1038/nmeth.1843
