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Nature Methods 6, 411 - 412 (2009)
doi:10.1038/nmeth.f.255

A stress test for mass spectrometry–based proteomics

Ruedi Aebersold1

  1. Ruedi Aebersold is at the Institute of Molecular Systems Biology, Eidgenössische Technische Hochschule Zurich, Faculty of Science, University of Zurich, Switzerland, and Institute for Systems Biology, Seattle, Washington, USA.


A multilaboratory study attempts to dispel some of the notions of the irreproducibility of mass spectrometry–based proteomics by pinpointing where the methodological problems are and where challenges remain.

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