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Nature Methods 6, 320–321 (1 May 2009) | doi:10.1038/nmeth0509-320b

Sequence is not everything

Natalie de Souza

Think of the structure of DNA, and what most probably comes to mind is the iconic double helix. Or, if you are a bioinformatician, like Elliott Margulies at the National Human Genome Research Institute, you may be prone to thinking of DNA as a string of characters on a computer screen.