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| Editorial | Top |
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Structural genomics in the spotlight p115
doi:10.1038/nmeth0208-115
Abstract | Full text | PDF
(56K)
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| Correspondence | Top |
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What ID is, beyond what it is not p117
Lee Turnpenny
doi:10.1038/nmeth0208-117a
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(80K)
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Reannotation of array probes at NCBI's GEO database p117
Tanya Barrett & Ron Edgar
doi:10.1038/nmeth0208-117b
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(80K)
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ALEXA: a microarray design platform for alternative expression analysis p118
Malachi Griffith, Michelle J Tang, Obi L Griffith, Ryan D Morin, Susanna Y Chan, Jennifer K Asano, Thomas Zeng, Stephane Flibotte, Adrian Ally, Agnes Baross, Martin Hirst, Steven J M Jones, Gregg B Morin, Isabella T Tai & Marco A Marra
doi:10.1038/nmeth0208-118
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(79K)
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MAPAS: a tool for predicting membrane-contacting protein surfaces p119
Yuriy Sharikov, Ross C Walker, Jerry Greenberg, Valentina Kouznetsova, Sanjay K Nigam, Mark A Miller, Eliezer Masliah & Igor F Tsigelny
doi:10.1038/nmeth0208-119
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(119K)
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| Research Highlights | Top |
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Snapshots of mouse development p121
Natalie de Souza
doi:10.1038/nmeth0208-121
Abstract | Full text | PDF
(123K)
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When microRNAs activate translation pp122 - 123
Nicole Rusk
doi:10.1038/nmeth0208-122a
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(145K)
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Gathering a bouquet of miRNA targets pp122 - 123
Katherine Stevens
doi:10.1038/nmeth0208-122b
Abstract | Full text | PDF
(145K)
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News in brief p123
doi:10.1038/nmeth0208-123
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(82K)
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Microfluidics and a garden hose p124
Daniel Evanko
doi:10.1038/nmeth0208-124
Abstract | Full text | PDF
(135K)
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Another handle for RNA p126
Irene Kaganman
doi:10.1038/nmeth0208-126
Abstract | Full text | PDF
(176K)
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| Commentary | Top |
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Structural genomics: from genes to structures with valuable materials and many questions in between pp129 - 132
Brian G Fox, Celia Goulding, Michael G Malkowski, Lance Stewart & Ashley Deacon
doi:10.1038/nmeth0208-129
Abstract | Full text | PDF
(129K)
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| News and Views | Top |
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How the sum of its parts gets greater than the whole pp133 - 134
Mario Brameshuber & Gerhard J Schütz
doi:10.1038/nmeth0208-133
Abstract | Full text | PDF
(122K)
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| Review | Top |
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Protein production and purification pp135 - 146
Structural Genomics Consortium, Architecture et Fonction des Macromolécules Biologiques, Berkeley Structural Genomics Center, China Structural Genomics Consortium, Integrated Center for Structure and Function Innovation, Israel Structural Proteomics Center, Joint Center for Structural Genomics, Midwest Center for Structural Genomics, New York Structural GenomiX Research Center for Structural Genomics, Northeast Structural Genomics Consortium, Oxford Protein Production Facility, Protein Sample Production Facility, Max Delbrück Center for Molecular Medicine, RIKEN Structural Genomics/Proteomics Initiative & SPINE2-Complexes
Published online: 30 January 2008 | doi:10.1038/nmeth.f.202
Abstract | Full text | PDF
(294K)
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| Perspective | Top |
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Protein crystallization: from purified protein to diffraction-quality crystal pp147 - 153
Naomi E Chayen & Emmanuel Saridakis
Published online: 30 January 2008 | doi:10.1038/nmeth.f.203
Abstract | Full text | PDF
(490K)
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| Brief Communications | Top |
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High-density mapping of single-molecule trajectories with photoactivated localization microscopy pp155 - 157
Suliana Manley, Jennifer M Gillette, George H Patterson, Hari Shroff, Harald F Hess, Eric Betzig & Jennifer Lippincott-Schwartz
Published online: 13 January 2008 | doi:10.1038/nmeth.1176
Abstract | Full text | PDF
(361K)
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Highly inclined thin illumination enables clear single-molecule imaging in cells pp159 - 161
Makio Tokunaga, Naoko Imamoto & Kumiko Sakata-Sogawa
Published online: 06 January 2008 | doi:10.1038/nmeth1171
Abstract | Full text | PDF
(218K)
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Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies pp163 - 165
Xiaodong Zhang, Chunguang Guo, Yueting Chen, Hennady P Shulha, Michael P Schnetz, Thomas LaFramboise, Cynthia F Bartels, Sanford Markowitz, Zhiping Weng, Peter C Scacheri & Zhenghe Wang
Published online: 06 January 2008 | doi:10.1038/nmeth1170
Abstract | Full text | PDF
(241K)
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Plasmid-chromosome shuffling for non-deletion alleles in yeast pp167 - 169
Zhiwei Huang, Richard S Sucgang, Yu-yi Lin, Xiaomin Shi, Jef D Boeke & Xuewen Pan
Published online: 13 January 2008 | doi:10.1038/nmeth.1173
Abstract | Full text | PDF
(172K)
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A secreted luciferase for ex vivo monitoring of in vivo processes pp171 - 173
Thomas Wurdinger, Christian Badr, Lisa Pike, Ruben de Kleine, Ralph Weissleder, Xandra O Breakefield & Bakhos A Tannous
Published online: 20 January 2008 | doi:10.1038/nmeth.1177
Abstract | Full text | PDF
(313K)
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Printing protein arrays from DNA arrays pp175 - 177
Mingyue He, Oda Stoevesandt, Elizabeth A Palmer, Farid Khan, Olle Ericsson & Michael J Taussig
Published online: 20 January 2008 | doi:10.1038/nmeth.1178
Abstract | Full text | PDF
(297K)
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Pyrobayes: an improved base caller for SNP discovery in pyrosequences pp179 - 181
Aaron R Quinlan, Donald A Stewart, Michael P Strömberg & Gábor T Marth
Published online: 13 January 2008 | doi:10.1038/nmeth.1172
Abstract | Full text | PDF
(189K)
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| Articles | Top |
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Whole-genome sequencing and variant discovery in C. elegans pp183 - 188
LaDeana W Hillier, Gabor T Marth, Aaron R Quinlan, David Dooling, Ginger Fewell, Derek Barnett, Paul Fox, Jarret I Glasscock, Matthew Hickenbotham, Weichun Huang, Vincent J Magrini, Ryan J Richt, Sacha N Sander, Donald A Stewart, Michael Stromberg, Eric F Tsung, Todd Wylie, Tim Schedl, Richard K Wilson & Elaine R Mardis
Published online: 20 January 2008 | doi:10.1038/nmeth.1179
Abstract | Full text | PDF
(173K)
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Genetic manipulation of adult mouse neurogenic niches by in vivo electroporation pp189 - 196
Fanie Barnabé-Heider, Konstantinos Meletis, Malin Eriksson, Olaf Bergmann, Hanna Sabelström, Michael A Harvey, Harald Mikkers & Jonas Frisén
Published online: 20 January 2008 | doi:10.1038/nmeth.1174
Abstract | Full text | PDF
(1,130K)
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High-speed, low-photodamage nonlinear imaging using passive pulse splitters pp197 - 202
Na Ji, Jeffrey C Magee & Eric Betzig
Published online: 20 January 2008 | doi:10.1038/nmeth.1175
Abstract | Full text | PDF
(826K)
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| Technology Feature | Top |
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Structural genomics: inside a protein structure initiative center pp203 - 207
Nathan Blow
doi:10.1038/nmeth0208-203
Abstract | Full text | PDF
(598K)
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| Application Notes | Top |
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Finding new protein interactions using the DUALhunter system
Natalie Möckli, Anna Deplazes & Daniel Auerbach
Abstract | Full text | PDF
(223K)
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MicroRNA quantitation from a single cell by PCR using SYBR® Green detection and LNA-based primers
Marie-Louise Lunn, Peter Mouritzen, Kirsten Faber & Nana Jacobsen
Abstract | Full text | PDF
(238K)
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