Abstract
By combining activity-based proteomics and metabolomics, researchers have developed a new systems biology strategy for characterizing enzymes in the context of metabolic networks.
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References
Chiang, K.P. et al. An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling. Chem. Biol. 13, 1041–1050 (2006).
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Doerr, A. Annotating the unannotated. Nat Methods 4, 8–9 (2007). https://doi.org/10.1038/nmeth0107-8b
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DOI: https://doi.org/10.1038/nmeth0107-8b