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Detection of individual gas molecules adsorbed on graphene

Abstract

The ultimate aim of any detection method is to achieve such a level of sensitivity that individual quanta of a measured entity can be resolved. In the case of chemical sensors, the quantum is one atom or molecule. Such resolution has so far been beyond the reach of any detection technique, including solid-state gas sensors hailed for their exceptional sensitivity1,2,3,4. The fundamental reason limiting the resolution of such sensors is fluctuations due to thermal motion of charges and defects5, which lead to intrinsic noise exceeding the sought-after signal from individual molecules, usually by many orders of magnitude. Here, we show that micrometre-size sensors made from graphene are capable of detecting individual events when a gas molecule attaches to or detaches from graphene’s surface. The adsorbed molecules change the local carrier concentration in graphene one by one electron, which leads to step-like changes in resistance. The achieved sensitivity is due to the fact that graphene is an exceptionally low-noise material electronically, which makes it a promising candidate not only for chemical detectors but also for other applications where local probes sensitive to external charge, magnetic field or mechanical strain are required.

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Figure 1: Sensitivity of graphene to chemical doping.
Figure 2: Constant mobility of charge carriers in graphene with increasing chemical doping.
Figure 3: Single-molecule detection.

References

  1. Moseley, P. T. Solid state gas sensors. Meas. Sci. Technol. 8, 223–237 (1997).

    Article  CAS  Google Scholar 

  2. Capone, S. et al. Solid state gas sensors: State of the art and future activities. J. Optoelect. Adv. Mater. 5, 1335–1348 (2003).

    CAS  Google Scholar 

  3. Kong, J. et al. Nanotube molecular wires as chemical sensors. Science 287, 622–625 (2000).

    Article  CAS  Google Scholar 

  4. Collins, P. G., Bradley, K., Ishigami, M. & Zettl, A. Extreme oxygen sensitivity of electronic properties of carbon nanotubes. Science 287, 1801–1804 (2000).

    Article  CAS  Google Scholar 

  5. Dutta, P. & Horn, P. M. Low-frequency fluctuations in solids: 1/f noise. Rev. Mod. Phys. 53, 497–516 (1981).

    Article  CAS  Google Scholar 

  6. Geim, A. K. & Novoselov, K. S. The rise of graphene. Nature Mater. 6, 183–191 (2007).

    Article  CAS  Google Scholar 

  7. Novoselov, K. S. et al. Two dimensional atomic crystals. Proc. Natl Acad. Sci. USA 102, 10451–10453 (2005).

    Article  CAS  Google Scholar 

  8. Novoselov, K. S. et al. Two dimensional gas of massless Dirac fermions in graphene. Nature 438, 197–200 (2005).

    Article  CAS  Google Scholar 

  9. Zhang, Y., Tan, J. W., Stormer, H. L. & Kim, P. Experimental observation of the quantum Hall effect and Berry’s phase in graphene. Nature 438, 201–204 (2005).

    Article  CAS  Google Scholar 

  10. Dresselhaus, M. S. & Dresselhaus, G. Intercalation compounds of graphite. Adv. Phys. 51, 1–186 (2002).

    Article  CAS  Google Scholar 

  11. Ando, T. Screening effect and impurity scattering in monolayer graphene. J. Phys. Soc. Jpn. 75, 074716 (2006).

    Article  Google Scholar 

  12. Nomura, K. & MacDonald, A. H. Quantum Hall ferromagnetism in graphene. Phys. Rev. Lett. 96, 256602 (2006).

    Article  Google Scholar 

  13. Hwang, E. H., Adam, S. & Das Sarma, S. Carrier transport in two-dimensional graphene layers. Phys. Rev. Lett. 98, 186806 (2007).

    Article  CAS  Google Scholar 

  14. Morozov, S. V. et al. Strong suppression of weak localization in graphene. Phys. Rev. Lett. 97, 016801 (2006).

    Article  CAS  Google Scholar 

  15. Meyer, J. C. et al. The structure of suspended graphene sheets. Nature 446, 60–63 (2007).

    Article  CAS  Google Scholar 

  16. Sheehan, P. E. & Whitman, L. J. Detection limits for nanoscale biosensors. Nano Lett. 5, 803–807 (2005).

    Article  CAS  Google Scholar 

  17. Berger, C. et al. Electronic confinement and coherence in patterned epitaxial graphene. Science 312, 1191–1196 (2006).

    Article  CAS  Google Scholar 

  18. Ohta, T., Bostwick, A., Seyller, T., Horn, K. & Rotenberg, E. Controlling the electronic structure of bilayer graphene. Science 313, 951–954 (2006).

    Article  CAS  Google Scholar 

  19. Barbolina, I. I. et al. Submicron sensors of local electric field with single-electron resolution at room temperature. Appl. Phys. Lett. 88, 013901 (2006).

    Article  Google Scholar 

  20. Bunch, J. S. et al. Electromechanical resonators from graphene sheets. Science 315, 490–493 (2007).

    Article  CAS  Google Scholar 

  21. Zhou, C., Kong, J., Yenilmez, E. & Dai, H. Modulated chemical doping of individual carbon nanotubes. Science 290, 1552–1555 (2000).

    Article  CAS  Google Scholar 

  22. Obradovic, B. et al. Analysis of graphene nanoribbons as a channel material for field-effect transistors. Appl. Phys. Lett. 88, 142102 (2006).

    Article  Google Scholar 

Download references

Acknowledgements

We thank A. MacDonald, S. Das Sarma and V. Falko for illuminating discussions. This work was supported by the EPSRC (UK) and the Royal Society. M.I.K. acknowledges financial support from FOM (Netherlands).

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Authors and Affiliations

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Contributions

K.S.N. designed the experiment and carried out both experimental work and data analysis, A.K.G. suggested the research direction and wrote the manuscript, F.S. and P.B. made graphene devices, S.V.M. and E.W.H. helped with experiments and their analysis and M.I.K. provided theory support. All authors participated in discussions of the research.

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Correspondence to K. S. Novoselov.

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The authors declare no competing financial interests.

Supplementary information

Supplementary Information

Supplementary information, figures S1-S3 and supplementary equations (PDF 293 kb)

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Schedin, F., Geim, A., Morozov, S. et al. Detection of individual gas molecules adsorbed on graphene. Nature Mater 6, 652–655 (2007). https://doi.org/10.1038/nmat1967

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