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Nature Medicine 9, 1110 - 1111 (2003)
doi:10.1038/nm0903-1110

Salt and wounds: a new mechanism for neuropathic pain

Kevin Staley1

  1. Kevin Staley is in the Department of Pediatrics and Neurology, University of Colorado School of Medicine, 4200 E. 9th Ave, Denver, Colorado 80262, USA. e-mail: kevin.staley@uchsc.edu


Neuropathic pain syndromes such as phantom limb pain have remained enigmatic to patients, physicians and researchers alike. A new study reveals how nerve damage may alter the pain threshold and lead to such syndromes.


Few syndromes in medicine are more demoralizing to patient and physician than intractable pain. Chronic pain is termed neuropathic when the pain arises from an alteration in the function of either the peripheral or central sensory systems.

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