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| Scientific progress during the first 20 years of HIV research has been impressive. The commentary and review articles in this focus capture how far we have come and convey the state of the field at the start of the AIDS pandemic. |
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| Editorial | Top |
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20 years of HIV science p803
doi:10.1038/nm0703-803
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| News | Top |
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Backyard biodefense rouses extreme reactions p805
Bruce Diamond
doi:10.1038/nm0703-805
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(279K)
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SARS-struck nations step up surveillance efforts p806
Paroma Basu
doi:10.1038/nm0703-806a
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China enlists traditional meds for SARS p806
Paroma Basu
doi:10.1038/nm0703-806b
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Fishy asthma cure raises big stink in India p807
K. S. Jayaraman
doi:10.1038/nm0703-807a
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Europe's new tests let rabbits rest easy p807
Xavier Bosch
doi:10.1038/nm0703-807b
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Wait of the world falls on Bush's ambitious AIDS plan p808
Tabitha M Powledge
doi:10.1038/nm0703-808a
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(149K)
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Cancer fears stall trials for testosterone replacement p808
Laura Bonetta
doi:10.1038/nm0703-808b
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(149K)
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News In Brief p809
doi:10.1038/nm0703-809
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Profile: Hugo Barrera-Saldaña p810
Helen Pearson
doi:10.1038/nm0703-810
Abstract | Full text | PDF
(121K)
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| Correspondence | Top |
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A "futile cycle" induced by thiazolidinediones in human adipose tissue? pp811 - 812
Garry D Tan, Cyrille Debard, Claire Tiraby, Sandy M Humphreys, Keith N Frayn, Dominique Langin, Hubert Vidal
& Fredrik Karpe
doi:10.1038/nm0703-811
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(99K)
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Reply to "A "futile cycle" induced by thiazolidinediones in human adipose tissue?" p812
Hong-Ping Guan
& Mitchell A Lazar
doi:10.1038/nm0703-812
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(88K)
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Indian-born weapons for infectious diseases p813
G. Padmanaban
doi:10.1038/nm0703-813
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(83K)
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| Book Reviews | Top |
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From a Nobel Perspective p815
Reviewed by: Paul Greengard
doi:10.1038/nm0703-815
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(134K)
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Tales of a Hobbesian Cynic p816
Reviewed by: Josef P Rauschecker
doi:10.1038/nm0703-816
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(167K)
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The unhealthy Earth p817
Reviewed by: Joseph Grzymski
doi:10.1038/nm0703-817
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(137K)
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| News and Views | Top |
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Probing for prions: recognizing misfolded PrP pp819 - 820
Byron Caughey
doi:10.1038/nm0703-819
Abstract | Full text | PDF
(200K)
See also: Article by Paramithiotis et al. |
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Dengue immune response: low affinity, high febrility pp820 - 822
Raymond M Welsh
& Alan L Rothman
doi:10.1038/nm0703-820
Abstract | Full text | PDF
(144K)
See also: Article by Mongkolsapaya et al. |
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Angiogenesis inhibitors: motivators of metastasis? pp822 - 823
Patricia S Steeg
doi:10.1038/nm0703-822
Abstract | Full text | PDF
(306K)
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Letting antibodies get to your head pp823 - 825
Robert S Fujinami
& Thayne L Sweeten
doi:10.1038/nm0703-823
Abstract | Full text | PDF
(1,152K)
See also: Article by Kirvan et al. |
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Polyglutamine neurodegeneration: minding your Ps and Qs pp825 - 826
Henry Paulson
doi:10.1038/nm0703-825
Abstract | Full text | PDF
(394K)
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Rules of conduct for the cystic fibrosis anion channel pp827 - 828
Jeffrey J Wine
doi:10.1038/nm0703-827
Abstract | Full text | PDF
(148K)
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Building up the blood-brain barrier pp828 - 829
Peter Rieckmann
& Britta Engelhardt
doi:10.1038/nm0703-828
Abstract | Full text | PDF
(224K)
See also: Article by Lee et al. |
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Research notes p830
Charlotte Schubert
& Stacie Grossman
doi:10.1038/nm0703-830
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(122K)
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| Perspective | Top |
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CpG motifs: the active ingredient in bacterial extracts? pp831 - 835
Arthur M Krieg
doi:10.1038/nm0703-831
Abstract | Full text | PDF
(241K)
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| Foreword | Top |
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20 Years of HIV Science
Twenty years on p838
doi:10.1038/nm0703-838
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(26K)
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| Commentaries | Top |
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20 Years of HIV Science
HIV and AIDS: 20 years of science pp839 - 843
Anthony S Fauci
doi:10.1038/nm0703-839
Abstract | Full text | PDF
(1,539K)
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20 Years of HIV Science
The early years of HIV research: integrating clinical and basic research pp844 - 846
Françoise Barré-Sinoussi
doi:10.1038/nm0703-844
Abstract | Full text | PDF
(612K)
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20 Years of HIV Science
I have it! p845
doi:10.1038/nm0703-845
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(449K)
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| Reviews | Top |
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20 Years of HIV Science
Transmission, acute HIV-1 infection and the quest for strategies to prevent infection pp847 - 852
Melissa Pope
& Ashley T Haase
doi:10.1038/nm0703-847
Abstract | Full text | PDF
(3,646K)
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20 Years of HIV Science
HIV-1 pathogenesis pp853 - 860
Mario Stevenson
doi:10.1038/nm0703-853
Abstract | Full text | PDF
(3,422K)
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20 Years of HIV Science
Immunopathogenesis and immunotherapy in AIDS virus infections pp861 - 866
Norman L Letvin
& Bruce D Walker
doi:10.1038/nm0703-861
Abstract | Full text | PDF
(1,423K)
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20 Years of HIV Science
Twenty years of therapy for HIV-1 infection pp867 - 873
Roger J Pomerantz
& David L Horn
doi:10.1038/nm0703-867
Abstract | Full text | PDF
(3,707K)
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20 Years of HIV Science
HIV vaccines 1983−2003 pp874 - 880
Andrew J McMichael
& Tomas Hanke
doi:10.1038/nm0703-874
Abstract | Full text | PDF
(1,923K)
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20 Years of HIV Science
Accomplishments in HIV prevention science: implications for stemming the epidemic pp881 - 886
Ronald O Valdiserri, Lydia L Ogden
& Eugene McCray
doi:10.1038/nm0703-881
Abstract | Full text | PDF
(737K)
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| Commentary | Top |
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20 Years of HIV Science
HIV and AIDS: looking ahead pp887 - 891
Robin A Weiss
doi:10.1038/nm0703-887
Abstract | Full text | PDF
(745K)
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| Articles | Top |
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A prion protein epitope selective for the pathologically misfolded conformation pp893 - 899
Eustache Paramithiotis, Marc Pinard, Trebor Lawton, Sylvie LaBoissiere, Valerie L Leathers, Wen-Quan Zou, Lisa A Estey, Julie Lamontagne, Marty T Lehto, Leslie H Kondejewski, Gregory P Francoeur, Maria Papadopoulos, Ashkan Haghighat, Stephen J Spatz, Mark Head, Robert Will, James Ironside, Katherine O'Rourke, Quentin Tonelli, Harry C Ledebur, Avi Chakrabartty
& Neil R Cashman
Published online: 01 June 2003 | doi:10.1038/nm883
Abstract | Full text | PDF
(1,826K)
| Supplementary Information
See also: News and Views by Caughey |
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SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier pp900 - 906
Sae-Won Lee, Woo Jean Kim, Yoon Kyung Choi, Hyun Seok Song, Myung Jin Son, Irwin H. Gelman, Yung-Jin Kim
& Kyu-Won Kim
Published online: 15 June 2003 | doi:10.1038/nm889
Abstract | Full text | PDF
(1,461K)
See also: News and Views by Rieckmann & Engelhardt |
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RAGE mediates amyloid- peptide transport across the blood-brain barrier and accumulation in brain pp907 - 913
Rashid Deane, Shi Du Yan, Ram Kumar Submamaryan, Barbara LaRue, Suzana Jovanovic, Elizabeth Hogg, Deborah Welch, Lawrence Manness, Chang Lin, Jin Yu, Hong Zhu, Jorge Ghiso, Blas Frangione, Alan Stern, Ann Marie Schmidt, Don L Armstrong, Bernd Arnold, Birgit Liliensiek, Peter Nawroth, Florence Hofman, Mark Kindy, David Stern
& Berislav Zlokovic
Published online: 15 June 2003 | doi:10.1038/nm890
Abstract | Full text | PDF
(653K)
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Mimicry and autoantibody-mediated neuronal cell signaling in Sydenham chorea pp914 - 920
Christine A Kirvan, Susan E Swedo, Janet S Heuser
& Madeleine W Cunningham
Published online: 22 June 2003 | doi:10.1038/nm892
Abstract | Full text | PDF
(612K)
| Supplementary Information
See also: News and Views by Fujinami & Sweeten |
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Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever pp921 - 927
Juthathip Mongkolsapaya, Wanwisa Dejnirattisai, Xiao-ning Xu, Sirijitt Vasanawathana, Nattaya Tangthawornchaikul, Aroonrung Chairunsri, Siraporn Sawasdivorn, Thaneeya Duangchinda, Tao Dong, Sarah Rowland-Jones, Pa-thai Yenchitsomanus, Andrew McMichael, Prida Malasit
& Gavin Screaton
Published online: 15 June 2003 | doi:10.1038/nm887
Abstract | Full text | PDF
(287K)
| Supplementary Information
See also: News and Views by Welsh & Rothman |
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Advantage of rare HLA supertype in HIV disease progression pp928 - 935
Elizabeth Trachtenberg, Bette Korber, Cristina Sollars, Thomas B Kepler, Peter T Hraber, Elizabeth Hayes, Robert Funkhouser, Michael Fugate, James Theiler, Yen S Hsu, Kevin Kunstman, Samuel Wu, John Phair, Henry Erlich
& Steven Wolinsky
Published online: 22 June 2003 | doi:10.1038/nm893
Abstract | Full text | PDF
(136K)
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Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1 pp936 - 943
Monica Autiero, Johannes Waltenberger, Didier Communi, Andrea Kranz, Lieve Moons, Diether Lambrechts, Jens Kroll, Stephane Plaisance, Maria De Mol, Françoise Bono, Stefanie Kliche, Guido Fellbrich, Kurt Ballmer-Hofer, Domenico Maglione, Ulrike Mayr-Beyrle, Mieke Dewerchin, Saskia Dombrowski, Danica Stanimirovic, Paul Van Hummelen, Christoph Dehio, Daniel J Hicklin, Graziella Persico, Jean-Marc Herbert, David Communi, Masabumi Shibuya, Désiré Collen, Edward M Conway
& Peter Carmeliet
Published online: 08 June 2003 | doi:10.1038/nm884
Abstract | Full text | PDF
(757K)
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Deletion of cytosolic phospholipase A2 promotes striated muscle growth pp944 - 951
Syed Haq, Heiko Kilter, Ashour Michael, Jingzang Tao, Eileen O'Leary, Xio Ming Sun, Brian Walters, Kausik Bhattacharya, Xin Chen, Lei Cui, Michele Andreucci, Anthony Rosenzweig, J. Luis Guerrero, Richard Patten, Ronglih Liao, Jeffery Molkentin, Michael Picard, Joseph V. Bonventre
& Thomas Force
Published online: 15 June 2003 | doi:10.1038/nm891
Abstract | Full text | PDF
(2,013K)
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Immunotherapy of established tumors using bone marrow transplantation with antigen gene−modified hematopoietic stem cells pp952 - 958
Yan Cui, Erin Kelleher, Erin Straley, Ephraim Fuchs, Kevin Gorski, Hyam Levitsky, Ivan Borrello, Curt I Civin, Stephen P Schoenberger, Linzhao Cheng, Drew M Pardoll
& Katharine A Whartenby
Published online: 01 June 2003 | doi:10.1038/nm882
Abstract | Full text | PDF
(332K)
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| Letters | Top |
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Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells pp959 - 963
Frédéric Mazurier, Monica Doedens, Olga I Gan
& John E Dick
Published online: 08 June 2003 | doi:10.1038/nm886
Abstract | Full text | PDF
(909K)
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BMP-7 counteracts TGF-1−induced epithelial-to-mesenchymal transition and reverses chronic renal injury pp964 - 968
Michael Zeisberg, Jun-ichi Hanai, Hikaru Sugimoto, Tadanori Mammoto, David Charytan, Frank Strutz
& Raghu Kalluri
Published online: 15 June 2003 | doi:10.1038/nm888
Abstract | Full text | PDF
(1,242K)
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| Technical Report | Top |
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Imaging 26S proteasome activity and inhibition in living mice pp969 - 973
Gary D Luker, Christina M Pica, Jiling Song, Kathryn E Luker
& David Piwnica-Worms
Published online: 22 June 2003 | doi:10.1038/nm894
Abstract | Full text | PDF
(343K)
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| Erratum | Top |
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Post-transplant Kaposi sarcoma originates from the seeding of donor-derived progenitors p975
P. Barozzi, M. Luppi, F. Facchetti, C. Mecucci, M. Alù, R. Sarid, V. Rasini, L. Ravazzini, E. Rossi, S. Festa, B. Crescenzi, D.G. Wolf, T.F. Schulz
& G. Torelli
doi:10.1038/nm0703-975a
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(39K)
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| Corrigendum | Top |
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Reply to "Tissue plasminogen activator and NMDA receptor cleavage" p975
Denis Vivien, Monica Fernández-Monreal, Olivier Nicole
& Alain Buisson
doi:10.1038/nm0703-975b
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(39K)
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| New on the Market | Top |
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New on the market p976
doi:10.1038/nm0703-976
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(124K)
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