A new model addresses the evolutionary mechanisms for antibiotic resistance and comes up with some grim forecasts. In the United States, resistance of Streptococcus pneumoniae to two commonly prescribed antibiotics is predicted to reach 41% by 2004 (pages 424–430).
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McGeer, A., Low, D. Is resistance futile?. Nat Med 9, 390–392 (2003). https://doi.org/10.1038/nm0403-390
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DOI: https://doi.org/10.1038/nm0403-390
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