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Corticosteroids and cardioprotection

New findings in mice suggest that corticosteroids mediate nitric oxide production in the endothelium, which in turn protects the heart against damage when deprived of oxygen. The mechanism explains, at least in part, the cardioprotective effects of these anti-inflammatory agents. (pages 473–479)

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Figure 1: Proposed mechanisms by which corticosteroids mediate cardioprotection.

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Thiemermann, C. Corticosteroids and cardioprotection. Nat Med 8, 453–455 (2002). https://doi.org/10.1038/nm0502-453

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