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Nature Medicine 7, 659 - 660 (2001)
doi:10.1038/89025
A dominant-negative therapy for anthrax
Stephen H. Leppla1
- Oral Infection and Immunity Branch National Institute of Dental & Craniofacial Research National Institutes of Health Bethesda, Maryland, USA
e-mail: Leppla@nih.gov
Abstract
The oligomeric structure of anthrax toxin might be exploited as a preventative or therapeutic vaccine.
Anthrax, a disease caused by the Gram-positive bacterium Bacillus anthracis, is rare in animals and even more rare in humans under normal circumstances. However, B. anthracis
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