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HIV-1 and Ebola virus: The getaway driver nabbed

In a healthy cell, the normal business of Tsg101 protein is as part of the machinery for protein trafficking. It now emerges that two deadly but unrelated viruses, HIV-1 and Ebola, both subvert Tsg101 as an essential step in their life cycles—exiting a cell to restart the cycle of infection. (pages 1313–1319)

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Figure 1: Getaway route: the same cellular factors are used by HIV-1 and Ebola virus to exit an infected cell.

Renee Lucas

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Luban, J. HIV-1 and Ebola virus: The getaway driver nabbed. Nat Med 7, 1278–1280 (2001). https://doi.org/10.1038/nm1201-1278

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