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A live-attenuated SIV vaccine inducing protection in healthy adult monkeys appears both safe and effective but may be lethal when given in high doses to newborns (pages 32–36).
Treatment of hypercholesterolemia by transplantation of xenogeneic hepatocytes presents new challenges and opportunities to immunologists (pages 48–53).
Evidence is accumulating that presenilin gene mutations may contribute to the pathogenesis of Alzheimer's disease by increasing amyloid β-protein production (pages 67–72).