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Nature Medicine 14, 910–912 (1 September 2008) | doi:10.1038/nm0908-910

Mitochondrial missile defense

Victor Nizet & Marc E Rothenberg

Eosinophils, a specialized granulocytic cell type derived from the bone marrow, are a biological and medical enigma. Recent attention has focused upon these curious cells with the emergence of a series of gastrointestinal disorders now referred to as eosinophil-associated gastrointestinal disorders (EGIDs).