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Technical Report

Nature Medicine 14, 213-221 (1 February 2008) | doi:10.1038/nm1684;

Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart

Harald C Ott , Thomas S Matthiesen , Saik-Kia Goh , Lauren D Black , Stefan M Kren , Theoden I Netoff & Doris A Taylor

About 3,000 individuals in the United States are awaiting a donor heart; worldwide, 22 million individuals are living with heart failure. A bioartificial heart is a theoretical alternative to transplantation or mechanical left ventricular support.

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