Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Volume 14 Issue 1, January 2008

In this issue (p 81), Christine Delprat and her colleagues report on the identification of a new, interleukin-17A-dependent mechanism of dendritic cell fusion in the rare disorder known as Langerhans cell histiocytosis. Image courtesy of Christine Delprat.

Editorial

  • A new proposal might allow drug makers to promote off-label uses of their products by distributing medical publications to US doctors. Stronger rules could assure that information—not propaganda—drives doctors' prescription practices.

    Editorial

    Advertisement

Top of page ⤴

News

  • Timeline of events...a brief look at the headlines from the past month

    News
  • These days, if you want to have your entire genome sequenced, you need to spend about a million dollars and wait for months. But the Archon X Prize for Genomics—an international competition for speedy gene mapping—might change this by giving companies a huge incentive to develop better DNA sequencing technologies. The $10 million prize, first announced in late 2006, was donated by Stewart Blusson, a philanthropist and mining multimillionaire. Marc Hodosh, senior director of the Archon X Prize, explains why genomics was chosen for an X Prize and predicts what lies ahead for the field.

    • Genevive Bjorn
    News
Top of page ⤴

Correspondence

Top of page ⤴

Book Review

Top of page ⤴

News & Views

  • T cells can turn back cancer, but they don't always reach tumor cells in sufficient numbers to do so. A close look at the cells of tumor blood vessels suggests a way to boost T cell migration in individuals with cancer (pages 28–36).

    • Michael H Kershaw
    News & Views
  • Vasopressin plays a vital part in homeostasis by regulating water excretion in the kidney. But it seems that vasopressin also dampens the inflammatory response to uropathogenic Escherichia coli—a finding that adds to a growing list of adverse actions of the 'antidiuretic hormone'.

    • Mark A Knepper
    • Robert A Star
    News & Views
  • Excess salt intake over many years can lead to high blood pressure. An essential signaling mechanism behind this effect is now uncovered (pages 64–68).

    • Wilhelm Schoner
    News & Views
  • Deep brain stimulation is increasingly used in the treatment of Parkinson's disease, essential tremor and other disorders, yet its mechanism of action remains unknown. New findings suggest that at least some of its action involves the release of adenosine, dampening tremors (pages 75–80).

    • Wael Asaad
    • Emad Eskandar
    News & Views
  • Propriospinal neurons, whose axons never leave the spinal cord, aid in recovery after spinal cord injury—even when all axons from the brain have been damaged (pages 69–74).

    • Dennis J Stelzner
    News & Views
  • Two hallmarks of lung fibrosis are vascular leakage and recruitment of fibroblasts into the alveoli. Lysophosphatidic acid is now implicated as a major regulator of both parameters (pages 45–54).

    • Klaus Ley
    • Alexander Zarbock
    News & Views
Top of page ⤴

Brief Communication

Top of page ⤴

Article

Top of page ⤴

Letter

Top of page ⤴

Technical Report

Top of page ⤴

Search

Quick links