The S6K1 kinase lies downstream of a signaling network crucial for muscle hypertrophy. It now seems that S6K1 also interacts with another kinase—AMPK—to integrate muscle-cell growth with metabolic regulation.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Glass, D.J. Int. J. Biochem. Cell Biol. 37, 1974–1984 (2005).
Nader, G.A. Int. J. Biochem. Cell Biol. 37, 1985–1996 (2005).
Bodine, S.C. et al. Nat. Cell Biol. 3, 1014–1019 (2001).
Mieulet, V. et al. Am. J. Physiol. Cell Physiol. 293, C712–C722 (2007).
Kahn, B.B., Alquier, T., Carling, D. & Hardie, D.G. Cell Metab. 1, 15–25 (2005).
Bolster, D.R., Crozier, S.J., Kimball, S.R. & Jefferson, L.S. J. Biol. Chem. 277, 23977–23980 (2002).
Chan, A.Y., Soltys, C.L., Young, M.E., Proud, C.G. & Dyck, J.R. J. Biol. Chem. 279, 32771–32779 (2004).
Inoki, K., Zhu, T. & Guan, K.L. Cell 115, 577–590 (2003).
Aguilar, V. et al. Cell Metab. 5, 476–487 (2007).
Ohanna, M. et al. Nat. Cell Biol. 7, 286–294 (2005).
Author information
Authors and Affiliations
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Nader, G. Muscle growth learns new tricks from an old dog. Nat Med 13, 1016–1018 (2007). https://doi.org/10.1038/nm0907-1016
Issue Date:
DOI: https://doi.org/10.1038/nm0907-1016