The Young and the Restless - p649

doi:10.1038/nm0607-649

Abstract - The Young and the Restless | Full Text - The Young and the Restless | PDF (147 KB) - The Young and the Restless

Sluggish approvals blocking Africans' access to bed nets - p651

Emma Marris

doi:10.1038/nm0607-651

Abstract - Sluggish approvals blocking Africans' access to bed nets | Full Text - Sluggish approvals blocking Africans' access to bed nets | PDF (195 KB) - Sluggish approvals blocking Africans' access to bed nets

Emergency trials of blood substitutes skirt ethical questions - p652

Andrea Anderson

doi:10.1038/nm0607-652

Abstract - Emergency trials of blood substitutes skirt ethical questions | Full Text - Emergency trials of blood substitutes skirt ethical questions | PDF (146 KB) - Emergency trials of blood substitutes skirt ethical questions

London hospital launches infectious disease 'biobank' - p653

Narelle Towie

doi:10.1038/nm0607-653a

Abstract - London hospital launches infectious disease 'biobank' | Full Text - London hospital launches infectious disease 'biobank' | PDF (202 KB) - London hospital launches infectious disease 'biobank'

Is it possible to make a Cox-2 inhibitor that's safe? - p653

doi:10.1038/nm0607-653b

Abstract - Is it possible to make a Cox-2 inhibitor that's safe? | Full Text - Is it possible to make a Cox-2 inhibitor that's safe? | PDF (202 KB) - Is it possible to make a Cox-2 inhibitor that's safe?

AIDS vaccine group expands operations in New York - p654

Alisa Opar

doi:10.1038/nm0607-654a

Abstract - AIDS vaccine group expands operations in New York | Full Text - AIDS vaccine group expands operations in New York | PDF (101 KB) - AIDS vaccine group expands operations in New York

Fertility clinics cashing in on risky immune tests, expert warns - p654

Michael Hopkin

doi:10.1038/nm0607-654b

Abstract - Fertility clinics cashing in on risky immune tests, expert warns | Full Text - Fertility clinics cashing in on risky immune tests, expert warns | PDF (101 KB) - Fertility clinics cashing in on risky immune tests, expert warns

Profile: Peter Doherty - p655

Apoorva Mandavilli

doi:10.1038/nm0607-655

Abstract - Profile: Peter Doherty | Full Text - Profile: Peter Doherty | PDF (178 KB) - Profile: Peter Doherty

News in brief - pp656 - 657

doi:10.1038/nm0607-656

Full Text - News in brief | PDF (729 KB) - News in brief

Paging all doctors - pp658 - 659

Tinker Ready

doi:10.1038/nm0607-658

Abstract - Paging all doctors | Full Text - Paging all doctors | PDF (243 KB) - Paging all doctors

Reply to 'Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities' - p661

Sheila M Gardiner, John Keyte & Terence Bennett

doi:10.1038/nm0607-661a

Full Text - Reply to 'Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities' | PDF (94 KB) - Reply to 'Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities'

Reply to 'Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities' - pp661 - 662

Masayoshi Shichiri

doi:10.1038/nm0607-661b

Full Text - Reply to 'Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities' | PDF (116 KB) - Reply to 'Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities'

Reply to 'Critics slam Russian trial to test pig pancreas for diabetes' - pp662 - 663

Megan Sykes, Richard N. Pierson, III, Philip O'Connell, Anthony D'Apice, Peter Cowan, Emanuele Cozzi, Anthony Dorling, Bernhard Hering, Joseph Leventhal & Jean-Paul Soulillou

doi:10.1038/nm0607-662

Full Text - Reply to 'Critics slam Russian trial to test pig pancreas for diabetes' | PDF (105 KB) - Reply to 'Critics slam Russian trial to test pig pancreas for diabetes'

The ethics of medical progress - p665

Angelique M Reitsma reviews Innovation in Medical Technology: Ethical Issues and Challenges by

doi:10.1038/nm0607-665

Full Text - The ethics of medical progress | PDF (279 KB) - The ethics of medical progress

Heme moves to center stage in cerebral malaria - pp667 - 669

Nicholas H Hunt & Roland Stocker

doi:10.1038/nm0607-667

Abstract - Heme moves to center stage in cerebral malaria | Full Text - Heme moves to center stage in cerebral malaria | PDF (694 KB) - Heme moves to center stage in cerebral malaria

See also: Article by Pamplona et al.

Linking calcineurin activity to leukemogenesis - pp669 - 671

Martin R Müller & Anjana Rao

doi:10.1038/nm0607-669

Abstract - Linking calcineurin activity to leukemogenesis | Full Text - Linking calcineurin activity to leukemogenesis | PDF (192 KB) - Linking calcineurin activity to leukemogenesis

See also: Letter by Medyouf et al.

Retinaldehyde: more than meets the eye - pp671 - 673

Béatrice Desvergne

doi:10.1038/nm0607-671

Abstract - Retinaldehyde: more than meets the eye | Full Text - Retinaldehyde: more than meets the eye | PDF (307 KB) - Retinaldehyde: more than meets the eye

See also: Article by Ziouzenkova et al.

The hydrogen highway to reperfusion therapy - pp673 - 674

Katherine C Wood & Mark T Gladwin

doi:10.1038/nm0607-673

Abstract - The hydrogen highway to reperfusion therapy | Full Text - The hydrogen highway to reperfusion therapy | PDF (825 KB) - The hydrogen highway to reperfusion therapy

See also: Article by Ohsawa et al.

HER3 and mutant EGFR meet MET - pp675 - 677

Carlos L Arteaga

doi:10.1038/nm0607-675

Abstract - HER3 and mutant EGFR meet MET | Full Text - HER3 and mutant EGFR meet MET | PDF (1,887 KB) - HER3 and mutant EGFR meet MET

Research highlights - pp678 - 679

doi:10.1038/nm0607-678

Full Text - Research highlights | PDF (709 KB) - Research highlights

The US pandemic influenza implementation plan at six months - pp681 - 684

Stephen S Morse

doi:10.1038/nm1597

Full Text - The US pandemic influenza implementation plan at six months | PDF (130 KB) - The US pandemic influenza implementation plan at six months

Restoration of cone vision in a mouse model of achromatopsia - pp685 - 687

John J Alexander, Yumiko Umino, Drew Everhart, Bo Chang, Seok H Min, Qiuhong Li, Adrian M Timmers, Norman L Hawes, Ji-jing Pang, Robert B Barlow & William W Hauswirth

doi:10.1038/nm1596

Abstract - Restoration of cone vision in a mouse model of achromatopsia | Full Text - Restoration of cone vision in a mouse model of achromatopsia | PDF (203 KB) - Restoration of cone vision in a mouse model of achromatopsia | Supplementary information

Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals - pp688 - 694

Ikuroh Ohsawa, Masahiro Ishikawa, Kumiko Takahashi, Megumi Watanabe, Kiyomi Nishimaki, Kumi Yamagata, Ken-ichiro Katsura, Yasuo Katayama, Sadamitsu Asoh & Shigeo Ohta

doi:10.1038/nm1577

Abstract - Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals | Full Text - Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals | PDF (622 KB) - Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals | Supplementary information

See also: News and Views by Wood & Gladwin

Retinaldehyde represses adipogenesis and diet-induced obesity - pp695 - 702

Ouliana Ziouzenkova, Gabriela Orasanu, Molly Sharlach, Taro E Akiyama, Joel P Berger, Jason Viereck, James A Hamilton, Guangwen Tang, Gregory G Dolnikowski, Silke Vogel, Gregg Duester & Jorge Plutzky

doi:10.1038/nm1587

Abstract - Retinaldehyde represses adipogenesis and diet-induced obesity | Full Text - Retinaldehyde represses adipogenesis and diet-induced obesity | PDF (422 KB) - Retinaldehyde represses adipogenesis and diet-induced obesity | Supplementary information

See also: News and Views by Desvergne

Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria - pp703 - 710

Ana Pamplona, Ana Ferreira, József Balla, Viktória Jeney, György Balla, Sabrina Epiphanio, Ângelo Chora, Cristina D Rodrigues, Isabel Pombo Gregoire, Margarida Cunha-Rodrigues, Silvia Portugal, Miguel P Soares & Maria M Mota

doi:10.1038/nm1586

Abstract - Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria | Full Text - Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria | PDF (362 KB) - Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria | Supplementary information

See also: News and Views by Hunt & Stocker

T_H17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1 - pp711 - 718

Ahjoku Amadi-Obi, Cheng-Rong Yu, Xuebin Liu, Rashid M Mahdi, Grace Levy Clarke, Robert B Nussenblatt, Igal Gery, Yun Sang Lee & Charles E Egwuagu

doi:10.1038/nm1585

Abstract - T: H: 17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1 | Full Text - TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1 | PDF (451 KB) - TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1 | Supplementary information

Mast cells promote atherosclerosis by releasing proinflammatory cytokines - pp719 - 724

Jiusong Sun, Galina K Sukhova, Paul J Wolters, Min Yang, Shiro Kitamoto, Peter Libby, Lindsey A MacFarlane, Jon Mallen-St Clair & Guo-Ping Shi

doi:10.1038/nm1601

First paragraph - Mast cells promote atherosclerosis by releasing proinflammatory cytokines | Full Text - Mast cells promote atherosclerosis by releasing proinflammatory cytokines | PDF (361 KB) - Mast cells promote atherosclerosis by releasing proinflammatory cytokines | Supplementary information

Neutralization of staphylococcal enterotoxin B by soluble, high-affinity receptor antagonists - pp725 - 729

Rebecca A Buonpane, Hywyn R O Churchill, Beenu Moza, Eric J Sundberg, Marnie L Peterson, Patrick M Schlievert & David M Kranz

doi:10.1038/nm1584

First paragraph - Neutralization of staphylococcal enterotoxin B by soluble, high-affinity receptor antagonists | Full Text - Neutralization of staphylococcal enterotoxin B by soluble, high-affinity receptor antagonists | PDF (364 KB) - Neutralization of staphylococcal enterotoxin B by soluble, high-affinity receptor antagonists | Supplementary information

Abrogation of nuclear receptors Nr4a3 andNr4a1 leads to development of acute myeloid leukemia - pp730 - 735

Shannon E Mullican, Shuo Zhang, Marina Konopleva, Vivian Ruvolo, Michael Andreeff, Jeffrey Milbrandt & Orla M Conneely

doi:10.1038/nm1579

First paragraph - Abrogation of nuclear receptors : : Nr4a3: : and: : Nr4a1: : leads to development of acute myeloid leukemia | Full Text - Abrogation of nuclear receptors Nr4a3 andNr4a1 leads to development of acute myeloid leukemia | PDF (426 KB) - Abrogation of nuclear receptors Nr4a3 andNr4a1 leads to development of acute myeloid leukemia | Supplementary information

Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia - pp736 - 741

Hind Medyouf, Hélène Alcalde, Caroline Berthier, Marie Claude Guillemin, Nuno R dos Santos, Anne Janin, Didier Decaudin, Hugues de Thé & Jacques Ghysdael

doi:10.1038/nm1588

First paragraph - Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia | Full Text - Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia | PDF (722 KB) - Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia | Supplementary information

See also: News and Views by Müller & Rao

Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment - pp742 - 747

Zhenyu Ju, Hong Jiang, Maike Jaworski, Chozhavendan Rathinam, Anne Gompf, Christoph Klein, Andreas Trumpp & K Lenhard Rudolph

doi:10.1038/nm1578

First paragraph - Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment | Full Text - Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment | PDF (453 KB) - Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment | Supplementary information

The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas - pp748 - 753

Eva Hernando, Elizabeth Charytonowicz, Maria E Dudas, Silvia Menendez, Igor Matushansky, Joslyn Mills, Nicholas D Socci, Nille Behrendt, Li Ma, Robert G Maki, Pier Paolo Pandolfi & Carlos Cordon-Cardo

doi:10.1038/nm1560

Abstract - The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas | Full Text - The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas | PDF (625 KB) - The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas | Supplementary information

An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS - pp754 - 759

Rishi Rakhit, Janice Robertson, Christine Vande Velde, Patrick Horne, Deborah M Ruth, Jennifer Griffin, Don W Cleveland, Neil R Cashman & Avijit Chakrabartty

doi:10.1038/nm1559

Abstract - An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS | Full Text - An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS | PDF (470 KB) - An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS | Supplementary information