News and Views


Nature Medicine 13, 284 - 285 (2007)
doi:10.1038/nm0307-284

Mycobacterium tuberculosis virulence: lipids inside and out

Sabine Ehrt1 & Dirk Schnappinger1

  1. The authors are in the Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, New York 10021, USA. e-mail: sae2004@med.cornell.edu or e-mail: dis2003@med.cornell.edu


During infections, Mycobacterium tuberculosis has to acquire nutrients and resist host defense. Lipids are important for both: host-derived lipids provide food, whereas pathogen-derived lipids mediate immune suppression.

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