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Nature Medicine 13, 1277 - 1278 (2007)
doi:10.1038/nm1107-1277

Reply to 'Microarrays: retracing steps'

Anil Potti1 & Joseph R Nevins1

  1. Duke Institute for Genome Sciences and Policy, Durham, North Carolina 27708, USA. e-mail: j.nevins@duke.edu

We appreciate the interest that Coombes et al.1 have shown in our reported results and agree that an algorithm that tracks the results of the various steps would be useful in such complex analyses. Unfortunately, they have not followed our methods in several crucial contexts and have made unjustified conclusions in others, and as a result their interpretation of our process is flawed.

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