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Bone-breaking cancer treatment

Nature Medicine volume 13, pages 25–26 (2007)Cite this article

A drug used to counteract low white blood cell counts in individuals with breast cancer may also be inducing bone metastases (pages 26–27).

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Figure 1: Breast cancer cells produce factors such as PTHrP and GM-CSF, which enhance the formation of osteoclasts.

Katie Ris

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  1. Center for Bone Biology at the University of Pittsburgh Medical Center and the Myeloma Program of the University of Pittsburgh Cancer Institute, VA Pittsburgh Healthcare System, R & D 151U, University Drive C, Pittsburgh, 15240, Pennsylvania, USA

    G David Roodman

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Roodman, G. Bone-breaking cancer treatment. Nat Med 13, 25–26 (2007). https://doi.org/10.1038/nm0107-25

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