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Brief Communication
Nature Medicine - 12, 1023 - 1026 (2006)
Published online: 13 August 2006; | doi:10.1038/nm1462

Role of deficient type III interferon-lambda production in asthma exacerbations

Marco Contoli, Simon D Message, Vasile Laza-Stanca, Michael R Edwards, Peter A B Wark, Nathan W Bartlett, Tatiana Kebadze, Patrick Mallia, Luminita A Stanciu, Hayley L Parker, Louise Slater, Anita Lewis-Antes, Onn M Kon, Stephen T Holgate, Donna E Davies, Sergei V Kotenko, Alberto Papi & Sebastian L Johnston

Supplementary Fig. 1 (pdf 812K)
IFN-lambdas are induced by rhinovirus infection of bronchial epithelial cells, monocytes and macrophages.

Supplementary Fig. 2 (pdf 640K)
IFN-lambdas induce IFN-stimulated genes in and protect bronchial epithelial cells against rhinovirus infection in vitro.

Supplementary Table 1 (pdf 160K)
Demographic data for patients entering the clinical studies.

Supplementary Methods (pdf 156K)

Supplementary Note (pdf 48K)


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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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