Nature Medicine
- 12, 1075 - 1080 (2006)
Published online: 6 August 2006; | doi:10.1038/nm1459
Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosisMurray C H Clarke, Nichola Figg, Janet J Maguire, Anthony P Davenport, Martin Goddard, Trevor D Littlewood & Martin R Bennett Supplementary Fig. 1 (pdf 136k)
Generation and characterization of transgenic mice. Supplementary Fig. 2 (pdf 904k)
Genotyping of Tgln2-HBEGF and Tgln2-HBEGF Apoe-/- mice. Supplementary Fig. 3 (pdf 96k)
Administration of DT induces VSMC-specific apoptosis in Tgln2-HBEGF mice. Supplementary Fig. 4 (pdf 172k)
Administration of DT does not induce nonspecific SMC loss in SM22 -hDTR mice. Supplementary Fig. 5 (pdf 152k)
VSMC apoptosis does not induce lymphocyte infiltration or expression of MCP-1/JE. Supplementary Fig. 6 (pdf 156k)
VSMC apoptosis induces vulnerable plaques in brachiocephalic arteries. Supplementary Fig. 7 (pdf 84k)
VSMC apoptosis increases serum IL-6.
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