Nature Medicine
- 12, 939 - 944 (2006)
Published online: 23 July 2006; | doi:10.1038/nm1447
Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinomaPremal H Thaker, Liz Y Han, Aparna A Kamat, Jesusa M Arevalo, Rie Takahashi, Chunhua Lu, Nicholas B Jennings, Guillermo Armaiz-Pena, James A Bankson, Murali Ravoori, William M Merritt, Yvonne G Lin, Lingegowda S Mangala, Tae Jin Kim, Robert L Coleman, Charles N Landen, Yang Li, Edward Felix, Angela M Sanguino, Robert A Newman, Mary Lloyd, David M Gershenson, Vikas Kundra, Gabriel Lopez-Berestein, Susan K Lutgendorf, Steven W Cole & Anil K Sood Supplementary Fig. 1 (pdf 220K)
Characterization of chronic stress in a mouse model. Supplementary Fig. 2 (pdf 96K)
Effect of chronic stress on in vivo ovarian cancer growth. Supplementary Fig. 3 (pdf 148K)
Effet of chronic stress and social isolation on angiogenesis. Supplementary Fig. 4 (pdf 116K)
Chronic stress does not promote angiogenesis in the  -adrenoreceptor null tumors. Supplementary Fig. 5 (pdf 176K)
Angiogenic cytokine expression in tumors from stressed mice. Supplementary Fig. 6 (pdf 132K)
Effect of stress hormones and various antagonists on endothelial cell migration and proliferation. Supplementary Fig. 7 (pdf 96K)
Effect of VEGF inhibitors on mouse body weight. Supplementary Fig. 8 (pdf 152K)
Chronic stress effects on mouse cardiac physiology, lymphangiogenesis and tumor cell proliferation. Supplementary Methods (pdf 136K)
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