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Nature Medicine 12, 747 - 751 (2006)
Published online: 28 June 2006 | doi:10.1038/nm0706-747

The amyloid code

Apoorva Mandavilli1

  1. Apoorva Mandavilli is senior news editor of Nature Medicine.


Is there a conspiracy afoot to keep one theory dominant in Alzheimer disease research? Maybe not, but as Apoorva Mandavilli discovers, it may still be high time for new ideas.


In the Church of the Holy Amyloid, the reigning deity is a 42–amino acid protein, thought to be the key to the mysteries that underlie Alzheimer disease. Amyloid has many believers—and like any good religion, a few staunch heretics who question its supremacy.

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