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| Editorial |  Top |
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Dear author, p1
doi:10.1038/nm0104-1
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| News | Top |
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Halted trial renews questions about cancer vaccines p3
Peter Vermij
& Martina Frei
doi:10.1038/nm0104-3
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(323K)
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China's new AIDS policy faces great wall of skepticism p4
I-han Chou
doi:10.1038/nm0104-4a
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AIDS infections, deaths hit record high in 2003 p4
Aparna Surendran
doi:10.1038/nm0104-4b
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(179K)
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Legal battle threatens universities' use of patented technologies p5
Tinker Ready
doi:10.1038/nm0104-5a
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(223K)
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The refrain in Spain is that Barbacid is to blame p5
Xavier Bosch
doi:10.1038/nm0104-5b
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New vaccines enter fray in fight against tuberculosis p6
Hannah Hoag
doi:10.1038/nm0104-6a
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Antibiotic resistance soars in Europe p6
Tony Sheldon
doi:10.1038/nm0104-6b
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List of 'prurient' research stirs fear, anger among US scientists p7
Vicki Brower
doi:10.1038/nm0104-7a
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Fatal flaw in baby formula sparks reform in Israeli ministry p7
Luba Vikhanski
doi:10.1038/nm0104-7b
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2003: The good, the bad and the unexpected p8
doi:10.1038/nm0104-8
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News In Brief p9
doi:10.1038/nm0104-9
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Profile: Marc Tessier-Lavigne p10
Apoorva Mandavilli
doi:10.1038/nm0104-10
Abstract | Full text | PDF
(129K)
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| Correspondence | Top |
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Properties of a disease-specific prion probe p11
Guy Gorochov
& Jean-Philippe Deslys
doi:10.1038/nm0104-11a
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Reply to "Properties of a disease-specific prion probe" pp11 - 12
Eustache Paramithiotis, Marc Pinard, Trebor Lawton, Sylvie LaBoissiere, Valerie L Leathers, Wen-Quan Zou, Lisa A Estey, Julie Lamontagne, Marty T Lehto, Leslie H Kondejewski, Gregory P Francoeur, Maria Papadopoulos, Ashkan Haghighat, Stephen J Spatz, Mark Head, Robert Will, James Ironside, Katherine O'Rourke, Quentin Tonelli, Harry C Ledebur, Avi Chakrabartty
& Neil R Cashman
doi:10.1038/nm0104-11b
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FasL, leukocytes and vascular modeling p12
Thomas A Ferguson
& Patrick M Stuart
doi:10.1038/nm0104-12
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Reply to "FasL, leukocytes and vascular modeling" p13
Susumu Ishida, Kenji Yamashiro, Tomohiko Usui
& Anthony P Adamis
doi:10.1038/nm0104-13
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| Book Reviews | Top |
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The making of a great scientist p15
Reviewed by: Thomas Lazar
doi:10.1038/nm0104-15
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Conflicts of interest p16
Reviewed by: Bernard Lo
doi:10.1038/nm0104-16
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| News and Views | Top |
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The idiotypic network in autoimmunity: antibodies that bind antibodies that bind antibodies pp17 - 18
Yehuda Shoenfeld
doi:10.1038/nm0104-17
Abstract | Full text | PDF
(206K)
See also: Article by Pendergraft et al. |
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THC: moderation during implantation pp19 - 20
Daniele Piomelli
doi:10.1038/nm0104-19
Abstract | Full text | PDF
(653K)
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HTLV-1 sweet-talks its way into cells pp20 - 21
Julie Overbaugh
doi:10.1038/nm0104-20
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(167K)
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No tolerance for depletion pp21 - 23
Hugh Auchincloss
doi:10.1038/nm0104-21
Abstract | Full text | PDF
(247K)
See also: Letter by Wu et al. |
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Embryonic stem cells: staying plastic on plastic pp23 - 24
Kinichi Nakashima, Sophia Colamarino
& Fred H Gage
doi:10.1038/nm0104-23
Abstract | Full text | PDF
(404K)
See also: Article by Sato et al. |
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Notch, the new muscle booster p24
Charlotte Schubert
doi:10.1038/nm0104-24
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(336K)
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Learning to take a deep breath—with BDNF pp25 - 26
George B Richerson
& John M Bekkers
doi:10.1038/nm0104-25
Abstract | Full text | PDF
(201K)
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Androgen receptor outwits prostate cancer drugs pp26 - 27
John T Isaacs
& William B Isaacs
doi:10.1038/nm0104-26
Abstract | Full text | PDF
(280K)
See also: Article by Chen et al. |
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Research Notes p28
doi:10.1038/nm0104-28
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(210K)
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| Brief Communications | Top |
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Escape of malaria parasites from host immunity requires CD4+CD25+ regulatory T cells pp29 - 30
Hajime Hisaeda, Yoichi Maekawa, Daiji Iwakawa, Hiroko Okada, Kunisuke Himeno, Kenji Kishihara, Shin-ichi Tsukumo
& Koji Yasutomo
Published online: 21 December 2003 | doi:10.1038/nm975
Abstract | Full text | PDF
(447K)
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Modifying quinolone antibiotics yields new anxiolytics pp31 - 32
Timothy B C Johnstone, Derk J Hogenkamp, Leanne Coyne, Jiping Su, Robert F Halliwell, Minhtam B Tran, Ryan F Yoshimura, Wen-Yen Li, Jeff Wang
& Kelvin W Gee
Published online: 30 November 2003 | doi:10.1038/nm967
Abstract | Full text | PDF
(113K)
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| Articles | Top |
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Molecular determinants of resistance to antiandrogen therapy pp33 - 39
Charlie D Chen, Derek S Welsbie, Chris Tran, Sung Hee Baek, Randy Chen, Robert Vessella, Michael G Rosenfeld
& Charles L Sawyers
Published online: 21 December 2003 | doi:10.1038/nm972
Abstract | Full text | PDF
(824K)
| Supplementary Information
See also: News and Views by Isaacs & Isaacs |
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Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor pp40 - 47
Li Hua Wang, Xiao Yi Yang, Xiaohu Zhang, Kelly Mihalic, Ying-Xin Fan, Weihua Xiao, O M Zack Howard, Ettore Appella, Andrew T Maynard
& William L Farrar
Published online: 14 December 2003 | doi:10.1038/nm969
Abstract | Full text | PDF
(1,276K)
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Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells pp48 - 54
Tianhong Wang, Guilian Niu, Marcin Kortylewski, Lyudmila Burdelya, Kenneth Shain, Shumin Zhang, Raka Bhattacharya, Dmitry Gabrilovich, Richard Heller, Domenico Coppola, William Dalton, Richard Jove, Drew Pardoll
& Hua Yu
Published online: 21 December 2003 | doi:10.1038/nm976
Abstract | Full text | PDF
(1,286K)
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Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor pp55 - 63
Noboru Sato, Laurent Meijer, Leandros Skaltsounis, Paul Greengard
& Ali H Brivanlou
Published online: 21 December 2003 | doi:10.1038/nm979
Abstract | Full text | PDF
(4,159K)
| Supplementary Information
See also: News and Views by Nakashima et al. |
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Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis pp64 - 71
Scott T Avecilla, Koichi Hattori, Beate Heissig, Rafael Tejada, Fang Liao, Koji Shido, David K Jin, Sergio Dias, Fan Zhang, Travis E Hartman, Neil R Hackett, Ronald G Crystal, Larry Witte, Daniel J. Hicklin, Peter Bohlen, Dan Eaton, David Lyden, Fredric de Sauvage
& Shahin Rafii
Published online: 21 December 2003 | doi:10.1038/nm973
Abstract | Full text | PDF
(3,421K)
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Autoimmunity is triggered by cPR-3(105−201), a protein complementary to human autoantigen proteinase-3 pp72 - 79
William F Pendergraft III, Gloria A Preston, Ruchir R Shah, Alexander Tropsha, Charles W Carter Jr, J Charles Jennette
& Ronald J Falk
Published online: 07 December 2003 | doi:10.1038/nm968
Abstract | Full text | PDF
(821K)
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See also: News and Views by Shoenfeld |
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Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway pp80 - 86
Akihiro Yasoda, Yasato Komatsu, Hideki Chusho, Takashi Miyazawa, Ami Ozasa, Masako Miura, Tatsuya Kurihara, Tomohiro Rogi, Shoji Tanaka, Michio Suda, Naohisa Tamura, Yoshihiro Ogawa
& Kazuwa Nakao
Published online: 14 December 2003 | doi:10.1038/nm971
Abstract | Full text | PDF
(2,467K)
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| Letters | Top |
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Homeostatic proliferation is a barrier to transplantation tolerance pp87 - 92
Zihao Wu, Steven J Bensinger, Jidong Zhang, Chuangqi Chen, Xueli Yuan, Xiaolun Huang, James F Markmann, Alireza Kassaee, Bruce R Rosengard, Wayne W Hancock, Mohamed H Sayegh
& Laurence A Turka
Published online: 30 November 2003 | doi:10.1038/nm965
Abstract | Full text | PDF
(294K)
See also: News and Views by Auchincloss |
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Fetal and adult human oligodendrocyte progenitor cell isolates myelinate the congenitally dysmyelinated brain pp93 - 97
Martha S Windrem, Marta C Nunes, William K Rashbaum, Theodore H Schwartz, Robert A Goodman, Guy McKhann II, Neeta S Roy
& Steven A Goldman
Published online: 21 December 2003 | doi:10.1038/nm974
Abstract | Full text | PDF
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| Technical Report | Top |
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A transgenic mouse model for monitoring endoplasmic reticulum stress pp98 - 102
Takao Iwawaki, Ryoko Akai, Kenji Kohno
& Masayuki Miura
Published online: 14 December 2003 | doi:10.1038/nm970
Abstract | Full text | PDF
(1,463K)
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| Corrigenda | Top |
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Corrigendum: Dendritic cell−induced autoimmune heart failure requires cooperation between adaptive and innate immunity p105
Urs Eriksson, Romeo Ricci, Lukas Hunziker, Michael O Kurrer, Gavin Y Oudit, Tania H Watts, Ivo Sonderegger, Kurt Bachmaier, Manfred Kopf
& Josef M Penninger
doi:10.1038/nm0104-105a
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Corrigendum: Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure p105
Mary Tang, Guang Wang, Ping Lu, Richard H Karas, Mark Aronovitz, Scott P Heximer, Kevin M Kaltenbronn, Kendall J Blumer, David P Siderovski, Yan Zhu
& Michael E Mendelsohn
doi:10.1038/nm0104-105b
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(42K)
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Corrigendum: Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates p105
Fernando D Camargo, Rahshaana Green, Yassemi Capetenaki, Kathyjo A Jackson
& Margaret A Goodell
doi:10.1038/nm0104-105c
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(42K)
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| New on the Market | Top |
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New on the market p106
doi:10.1038/nm0104-106
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(284K)
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