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| Editorial |  Top |
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Clinical investigation: An endangered science p281
Barbara J. Culliton
doi:10.1038/nm0495-281
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(138K)
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| Letters to the Editor | Top |
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Elevated plasma levels of TGF- 1 in patients with invasive prostate cancer pp282 - 284
Vesna Ivanovic, Arnold Melman, Brian Davis-Joseph, Mira Valcic
& Jan Geliebter
doi:10.1038/nm0495-282
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(478K)
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Coxsackie virus and diabetes revisited p284
David B. Jones
& Nigel W. Armstrong
doi:10.1038/nm0495-284
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(237K)
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| News | Top |
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AIDS drugs lurch towards market pp285 - 286
Fintan Steele
doi:10.1038/nm0495-285
Abstract | PDF
(237K)
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Role of genetics and criminal behaviour debated pp286 - 287
Nuala Moran
doi:10.1038/nm0495-286
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(293K)
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Electronic guide for clinicians p287
Gail Vines
doi:10.1038/nm0495-287a
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(175K)
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Plans to establish a national bioethics board in the US move ahead p287
Helen Gavaghan
doi:10.1038/nm0495-287b
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(174K)
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Nutritionist 'Rama' honoured p287
K.S. Jayaraman
doi:10.1038/nm0495-287c
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(175K)
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Anti-addiction drug ibogaine on trial pp288 - 289
Nancy Touchette
doi:10.1038/nm0495-288
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(293K)
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New Japanese IVF method finally made available in Japan pp289 - 290
Timo Hannay
doi:10.1038/nm0495-289
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(283K)
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Tailored therapy can lower costly Gaucher treatments p290
Jeffrey L. Fox
doi:10.1038/nm0495-290
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(188K)
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Government unveils plan to kick-start gene therapy R&D in Japan p291
Timo Hannay
doi:10.1038/nm0495-291
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(112K)
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Industry sceptical of new gene therapy review p292
Helen Gavaghan
doi:10.1038/nm0495-292a
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(145K)
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Male contraceptive with DMSO in trials pp292 - 293
K.S. Jayaraman
doi:10.1038/nm0495-292b
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(359K)
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French review research strategy p293
Catherine Tastemain
doi:10.1038/nm0495-293
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(232K)
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Funding for international center begins to pay dividends p294
K.S. Jayraman
doi:10.1038/nm0495-294a
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(205K)
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Boost for UK biomedical research p294
Nuala Moran
doi:10.1038/nm0495-294b
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(205K)
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| News and Views | Top |
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Assessing animal models of AIDS pp295 - 297
James Stott
& Neil Almond
doi:10.1038/nm0495-295
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(351K)
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Anatomical research lives! pp297 - 298
Van P. Thompson
doi:10.1038/nm0495-297
Abstract + references | PDF
(226K)
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Genetics and environment in Hodgkin's disease pp298 - 300
Henry T. Lynch
& Joseph N. Marcus
doi:10.1038/nm0495-298
Abstract + references | PDF
(319K)
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Molecular DIY with hairpins and hammerheads pp300 - 302
Saghir Akhtar, Helen James
& Ian Gibson
doi:10.1038/nm0495-300
Abstract + references | PDF
(471K)
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Testing for cancer genes: Decisions, decisions pp302 - 303
Katherine A. Schneider, Andrea Farkas Patenaude
& Judy E. Garber
doi:10.1038/nm0495-302
Abstract + references | PDF
(314K)
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CTL to HIV-1: Surrogates or sirens pp304 - 305
Bonnie J. Mathieson
doi:10.1038/nm0495-304
Abstract + references | PDF
(227K)
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Filling in the matrix of kidney disease pp305 - 306
Robert Bacallao
doi:10.1038/nm0495-305
Abstract + references | PDF
(241K)
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Sickle cell paths converge on hydroxyurea pp307 - 308
Orah S. Platt
doi:10.1038/nm0495-307
Abstract + references | PDF
(276K)
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| Review | Top |
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Molecular foundations of cancer: New targets for intervention pp309 - 320
Judith E. Karp
& Samuel Broder
doi:10.1038/nm0495-309
Abstract + references | PDF
(1,610K)
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| Articles | Top |
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HIV-1 recombinant poxvirus vaccine induces cross-protection against HIV-2 challenge in rhesus macaques pp321 - 329
Alash'le G. Abimiku, Genoveffa Franchini, James Tartaglia, Kristine Aldrich, Maria Myagkikh, Phillip D. Markham, Pele Chong, Michel Klein, Marie-Paule Kieny, Enzo Paoletti, Robert C. Gallo
& Marjorie Robert-Guroff
doi:10.1038/nm0495-321
Abstract + references | PDF
(1,219K)
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Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression pp330 - 336
Scott Koenig, Anthony J. Conley, Yambasu A. Brewah, Gary M. Jones, Simon Leath, Lynn J. Boots, Victoria Davey, Guiseppi Pantaleo, James F. Demarest, Charles Carter, Christine Wannebo, John R. Yannelli, Steven A. Rosenberg
& H. Clifford Lane
doi:10.1038/nm0495-330
Abstract + references | PDF
(1,492K)
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Bromocriptine in the treatment of alcoholics with the D2 dopamine receptor A1 allele pp337 - 341
Bruce R. Lawford, Ross McD. Young, John A. Rowell, Joan Qualichefski, Barbara H. Fletcher, Karl Syndulko, Terry Ritchie
& Ernest P. Noble
doi:10.1038/nm0495-337
Abstract + references | PDF
(665K)
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In utero surgery rescues neurological function at birth in sheep with spina bifida pp342 - 347
Martin Meuli, Claudia Meuli-Simmen, Grover M. Hutchins, Charles D. Yingling, Kathleen McBiles Hoffman, Michael R. Harrison
& N. Scott Adzick
doi:10.1038/nm0495-342
Abstract + references | PDF
(824K)
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Genetic instability occurs in the majority of young patients with colorectal cancer pp348 - 352
Bo Liu, Susan M. Farrington, Gloria M. Petersen, Stanley R. Hamilton, Ramon Parsons, Nickolas Papadopoulos, Takato Fujiwara, Jin Jen, Kenneth W. Ainzler, Andrew H. Wyllie, Bert Vogelstein
& Malcolm G. Dunlop
doi:10.1038/nm0495-348
Abstract + references | PDF
(714K)
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Long-term delivery of a lysosomal enzyme by genetically modified fibroblasts in dogs pp353 - 357
Philippe Moullier, Delphine Bohl, Jorge Cardoso, Jean Michel Heard
& Olivier D. Amos
doi:10.1038/nm0495-353
Abstract + references | PDF
(743K)
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The PKD1 gene produces a developmentally regulated protein in mesenchyme and vasculature pp359 - 364
Janet S. van Adelsberg
& Dale Frank
doi:10.1038/nm0495-359
Abstract + references | PDF
(707K)
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Tau protein directly interacts with the amyloid -protein precursor: Implications for Alzheimer's disease pp365 - 369
M.A. Smith, S.L. Siedlak, P.L. Richey, P. Mulvihill, J. Ghiso, B. Frangione, F. Tagliavini, G. Giaccone, O. Bugiani, D. Praprotnik, R.N. Kalaria
& G. Perry
doi:10.1038/nm0495-365
Abstract + references | PDF
(689K)
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High nitric oxide production in human paranasal sinuses pp370 - 373
J.O.N. Lundberg, T. Farkas-Szallasi, E. Weitzberg, J. Rinder, J. Lidholm, A. Änggåard, T. Hökfelt, J.M. Lundberg
& K. Alving
doi:10.1038/nm0495-370
Abstract + references | PDF
(834K)
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Association of hepatitis B surface antigen carriage with severe malaria in Gambian children pp374 - 375
Mark R. Thursz, Dominic Kwiatkowski, M Estée Torok, Catherine E.M. Allsopp, Brian M. Greenwood, Hilton C. Whittle, Howard C. Thomas
& Adrian V.S. Hill
doi:10.1038/nm0495-374
Abstract + references | PDF
(223K)
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| Book Reviews | Top |
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The Hostage Brain p377
doi:10.1038/nm0495-377
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(175K)
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Reports of note p378
doi:10.1038/nm0495-378
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(533K)
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| New Technology | Top |
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Functional magnetic resonance imaging depicts the brain in action pp379 - 381
Michael H. Buonocore
& Stephen T. Hecht
doi:10.1038/nm0495-379
References | PDF
(453K)
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On the market pp381 - 383
doi:10.1038/nm0495-381
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(472K)
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| Erratum | Top |
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Errata p384
doi:10.1038/nm0495-384
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(375K)
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