News and Views
Nature Genetics 40, 491 - 492 (2008)
doi:10.1038/ng0508-491
Principal component analysis of genetic data
David Reich1, Alkes L Price1 & Nick Patterson2
- David Reich and Alkes L. Price are at the Department of Genetics, Harvard Medical School, New Research Building, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.
- Nick Patterson is at the Broad Institute of Harvard and the Massachusetts Institute of Technology, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA. e-mail: reich@genetics.med.harvard.edu
Abstract
Principal component analysis (PCA) has been a useful tool for analysis of genetic data, particularly in studies of human migration. A new study finds evidence that the observed geographic gradients, traditionally thought to represent major historical migrations, may in fact have other interpretations.
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