News and Views
Nature Genetics 39, 708 - 710 (2007)
doi:10.1038/ng0607-708
'Unleashed' natural killers hinder HIV
Marcus Altfeld1 & Philip Goulder2
- Marcus Altfeld is at Partners AIDS Research Center, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, Massachusetts 02129, USA.
- Philip Goulder is at Partners AIDS Research Center and at the Department of Paediatrics, University of Oxford, Oxford OX1 3SY, UK. e-mail: Philip.Goulder@paediatrics.ox.ac.uk
Abstract
A new study reports that specific combinations of killer immunoglobulin-like receptor and HLA-B alleles influence AIDS progression and plasma HIV RNA levels in HIV-infected individuals. These results suggest that natural killer cells have an important role in recognizing and limiting HIV infection.
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