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Letter
Nature Genetics 39, 673–677 (1 May 2007) | doi:10.1038/ng2003
Impaired microRNA processing enhances cellular transformation and tumorigenesis
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Abstract
MicroRNAs (miRNAs) are a new class of small noncoding RNAs that post-transcriptionally regulate the expression of target mRNA transcripts. Many of these target mRNA transcripts are involved in proliferation, differentiation and apoptosis, processes commonly altered during tumorigenesis.
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