Three new reports leverage genome-wide studies to localize and replicate multiple independent variants strongly associated with prostate cancer on chromosome 8q24. These findings provide a significant advance toward deciphering the genetic basis of this disease, although further work is needed to clarify the biological mechanisms underlying these associations.
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Witte, J. Multiple prostate cancer risk variants on 8q24. Nat Genet 39, 579–580 (2007). https://doi.org/10.1038/ng0507-579
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DOI: https://doi.org/10.1038/ng0507-579
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