1. Ewan Birney is at the European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, United Kingdom.
   e-mail: birney@ebi.ac.uk

Abstract

A new study presents a comprehensive global analysis of the evolution of segmental duplications in the human genome. The authors identify the origin of ancestral duplication loci, regions of clustered duplicons, and evidence supporting a punctuated model of evolution.

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