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Letter
Nature Genetics 38, 583–588 (1 May 2006) | doi:10.1038/ng1787
Total insulin and IGF-I resistance in pancreatic |[beta]| cells causes overt diabetes
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Abstract
An appropriate β cell mass is pivotal for the maintenance of glucose homeostasis. Both insulin and IGF-1 are important in regulation of β cell growth and function (reviewed in ref.
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