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Letter
Nature Genetics 37, 601–606 (1 June 2005) | doi:10.1038/ng1565
Human recombination hot spots hidden in regions of strong marker association
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Abstract
The fine-scale distribution of meiotic recombination events in the human genome can be inferred from patterns of haplotype diversity in human populations but directly studied only by high-resolution sperm typing. Both approaches indicate that crossovers are heavily clustered into narrow recombination hot spots.
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