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The first steps in adaptive evolution

Nature Genetics volume 37, pages 342–343 (2005)Cite this article

The first empirical test of an evolutionary theory provides support for a mutational landscape model underlying the process of adaptation. The study shows that it is possible to predict at least the first step in an adaptive walk and also shows the importance of incorporating mutation bias in the fitness effects of mutations.

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Figure 1: A model bacteriophage takes its first adaptive step on a fitness landscape.

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Authors and Affiliations

  1. the Section of Integrative Biology and Institute for Cellular and Molecular Biology, University of Texas, Austin, 78712-0253, Texas, USA

    James J Bull

  2. the Department of Zoology, University of British Columbia, Vancouver, V6T 1Z4, British Columbia, Canada

    Sarah P Otto

Authors
  1. James J Bull
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  2. Sarah P Otto
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Bull, J., Otto, S. The first steps in adaptive evolution. Nat Genet 37, 342–343 (2005). https://doi.org/10.1038/ng0405-342

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