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News and Views
Nature Genetics  37, 1027 - 1028 (2005)
doi:10.1038/ng1005-1027

Stem cells, asymmetric division and cancer

Hans Clevers

Hans Clevers is in the Hubrecht Laboratory and Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, NL-3584, The Netherlands. clevers@niob.knaw.nl

Asymmetric division of stem cells results into two unequal daughter cells, only one of which resembles the parent stem cell. A new study provides genetic evidence in Drosophila melanogaster that the disturbance of this delicately balanced process in neuronal stem cells induces a cancer-like state.

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