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News and Views
Nature Genetics  36, 114 - 115 (2004)
doi:10.1038/ng0204-114

Close look at gene conversion hot spots

Jeffrey D Wall

Jeffrey D. Wall is in the Program in Molecular and Computational Biology at The University of Southern California, 1042 W. 36th Place, DRB 289, Los Angeles, California 90089, USA. jeffwall@usc.edu

New work has directly estimated male gene conversion rates in three regions of the human genome and identified gene conversion hot spots in the same locations as previously identified crossover hot spots. This work elucidates the fine-scale structure of linkage disequilibrium (LD) in the human genome and will be useful in association studies and other LD-based applications in population and human genetics.

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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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