TGF- signaling in tumor suppression and cancer progressionpp117 - 129 Rik Derynck, Rosemary J. Akhurst
& Allan Balmain doi:10.1038/ng1001-117 Abstract|Full text|PDF
(369K)
Intra-cytoplasmic sperm injection and infertilityp131 Malcolm J. Faddy, Sherman J. Silber
& Roger G. Gosden doi:10.1038/ng1001-131 Abstract|Full text|PDF
(48K)
An SSLP marker−anchored BAC framework map of the mouse genomepp133 - 134 Wei-Wen Cai, Chi-Wan Chow, Shamsha Damani, Simon G. Gregory, Marco Marra
& Allan Bradley doi:10.1038/ng1001-133 Abstract|Full text|PDF
(88K)
|Supplementary Information
Hypotrichosis with juvenile macular dystrophy is caused by a mutation in CDH3, encoding P-cadherinpp134 - 136 Eli Sprecher, Reuven Bergman, Gabriele Richard, Raziel Lurie, Stavit Shalev, Dan Petronius, Adel Shalata, Yefim Anbinder, Rina Leibu, Ido Perlman, Nadine Cohen
& Raymonde Szargel Published online: 04 September 2001|doi:10.1038/ng716 Abstract|Full text|PDF
(2,271K)
A role for MLH3 in hereditary nonpolyposis colorectal cancerpp137 - 138 Ying Wu, Maran J.W. Berends, Rolf H. Sijmons, Rob G.J. Mensink, Edwin Verlind, Krista A. Kooi, Tineke van der Sluis, Claudia Kempinga, Ate G.J. van der Zee, Harry Hollema, Charles H.C.M. Buys, Jan H. Kleibeuker
& Robert M.W. Hofstra doi:10.1038/ng1001-137 Abstract|Full text|PDF
(675K)
|Supplementary Information
Unexpectedly high rate of de novo constitutional t(11;22) translocations in sperm from normal malespp139 - 140 Hiroki Kurahashi
& Beverly S. Emanuel doi:10.1038/ng1001-139 Abstract|Full text|PDF
(639K)
|Supplementary Information
Mutation of PVRL1 is associated with sporadic, non-syndromic cleft lip/palate in northern Venezuelapp141 - 142 Mehmet A. Sözen, Koji Suzuki, Marie M. Tolarova, Tania Bustos, Jesús E. Fernández Iglesias
& Richard A. Spritz Published online: 17 September 2001|doi:10.1038/ng740 Abstract|Full text|PDF
(94K)
See also:News and Views by Murray
Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic diseasepp143 - 152 Tobey J. MacDonald, Kevin M. Brown, Bonnie LaFleur, Katia Peterson, Christopher Lawlor, Yidong Chen, Roger J. Packer, Philip Cogen
& Dietrich A. Stephan Published online: 04 September 2001|doi:10.1038/ng731 Abstract|Full text|PDF
(466K)
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosispp160 - 165 Yi Yang, Afif Hentati, Han-Xiang Deng, Omar Dabbagh, Toru Sasaki, Makito Hirano, Wu-Yen Hung, Karim Ouahchi, Jianhua Yan, Anser C. Azim, Natalie Cole, Generoso Gascon, Ayesha Yagmour, Mongi Ben-Hamida, Margaret Pericak-Vance, Fayçal Hentati
& Teepu Siddique doi:10.1038/ng1001-160 Abstract|Full text|PDF
(866K)
See also:News and Views by Shaw
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2pp166 - 173 Shinji Hadano, Collette K. Hand, Hitoshi Osuga, Yoshiko Yanagisawa, Asako Otomo, Rebecca S. Devon, Natsuki Miyamoto, Junko Showguchi-Miyata, Yoshinori Okada, Roshni Singaraja, Denise A. Figlewicz, Thomas Kwiatkowski, Betsy A. Hosler, Tally Sagie, Jennifer Skaug, Jamal Nasir, Robert H. Brown Jr, Stephen W. Scherer, Guy A. Rouleau, Michael R. Hayden
& Joh-E Ikeda doi:10.1038/ng1001-166 Abstract|Full text|PDF
(2,987K)
|Supplementary Information See also:News and Views by Shaw
Gene polymorphism in Netherton and common atopic diseasepp175 - 178 Andrew J. Walley, Stéphane Chavanas, Miriam F. Moffatt, Robert M. Esnouf, Baljinder Ubhi, Robert Lawrence, Kenny Wong, Gonçalo R Abecasis, E. Yvonne Jones, John I. Harper, Alain Hovnanian
& William O.C.M. Cookson Published online: 04 September 2001|doi:10.1038/ng728 Abstract|Full text|PDF
(104K)
|Supplementary Information
The T-box transcription factor gene TBX22 is mutated in X-linked cleft palate and ankyloglossiapp179 - 183 Claire Braybrook, Kit Doudney, Ana Carolina B. Marçano, Alfred Arnason, Arni Bjornsson, Michael A. Patton, Paul J. Goodfellow, Gudrun E. Moore
& Philip Stanier Published online: 17 September 2001|doi:10.1038/ng730 Abstract|Full text|PDF
(434K)
|Supplementary Information See also:News and Views by Murray
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily genepp184 - 188 Hidetoshi Date, Osamu Onodera, Hajime Tanaka, Kiyoshi Iwabuchi, Kazutoshi Uekawa, Shuichi Igarashi, Ryoko Koike, Tadashi Hiroi, Tatsuhiko Yuasa, Yutaka Awaya, Tetsuo Sakai, Tatsuya Takahashi, Hideki Nagatomo, Yoshiki Sekijima, Izumi Kawachi, Yoshihisa Takiyama, Masatoyo Nishizawa, Nobuyoshi Fukuhara, Kayoko Saito, Sumio Sugano
& Shoji Tsuji doi:10.1038/ng1001-184 Abstract|Full text|PDF
(501K)
|Supplementary Information
The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxinpp189 - 193 Maria-Céu Moreira, Clara Barbot, Nobutada Tachi, Naoki Kozuka, Eiji Uchida, Toby Gibson, Pedro Mendonça, Manuela Costa, José Barros, Takayuki Yanagisawa, Mitsunori Watanabe, Yoshio Ikeda, Masashi Aoki, Tetsuya Nagata, Paula Coutinho, Jorge Sequeiros
& Michel Koenig doi:10.1038/ng1001-189 Abstract|Full text|PDF
(549K)
|Supplementary Information
A radiation hybrid transcript map of the mouse genomepp194 - 200 Philip Avner, Thomas Bruls, Isabelle Poras, Lorraine Eley, Shahinaz Gas, Patricia Ruiz, Michael V. Wiles, Rita Sousa-Nunes, Ross Kettleborough, Amer Rana, Jean Morissette, Liz Bentley, Michelle Goldsworthy, Alison Haynes, Eifion Herbert, Lorraine Southam, Hans Lehrach, Jean Weissenbach, Giacomo Manenti, Patricia Rodriguez-Tome, Rosa Beddington, Sally Dunwoodie
& Roger D. Cox doi:10.1038/ng1001-194 Abstract|Full text|PDF
(932K)
A radiation hybrid map of mouse genespp201 - 205 Thomas J. Hudson, Deanna M. Church, Simon Greenaway, Huy Nguyen, April Cook, Robert G. Steen, William J. Van Etten, Andrew B. Castle, Mark A. Strivens, Pamela Trickett, Christine Heuston, Claire Davison, Anne Southwell, Rachel Hardisty, Anabel Varela-Carver, Andrew R. Haynes, Patricia Rodriguez-Tome, Hirofumi Doi, Minoru S.H. Ko, Joan Pontius, Lynn Schriml, Lukas Wagner, Donna Maglott, Steve D.M. Brown, Eric S. Lander, Greg Schuler
& Paul Denny doi:10.1038/ng1001-201 Abstract|Full text|PDF
(411K)
Disruption of Trrap causes early embryonic lethality and defects in cell cycle progressionpp206 - 211 Zdenko Herceg, Wolfgang Hulla, David Gell, Cyrille Cuenin, Matilde Lleonart, Stephen Jackson
& Zhao-Qi Wang Published online: 04 September 2001|doi:10.1038/ng725 Abstract|Full text|PDF
(1,189K)
Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenasepp212 - 216 Boris M. Hogema, Maneesh Gupta, Henry Senephansiri, Terry G. Burlingame, Melissa Taylor, Cornelis Jakobs, Ruud B. H. Schutgens, Wolfgang Froestl, O. Carter Snead, Ramon Diaz-Arrastia, Teodoro Bottiglieri, Markus Grompe
& K. Michael Gibson Published online: 04 September 2001|doi:10.1038/ng727 Abstract|Full text|PDF
(992K)
Intensely punctate meiotic recombination in the class II region of the major histocompatibility complexpp217 - 222 Alec J. Jeffreys, Liisa Kauppi
& Rita Neumann doi:10.1038/ng1001-217 Abstract|Full text|PDF
(192K)
See also:News and Views by Goldstein
Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn diseasepp223 - 228 John D. Rioux, Mark J. Daly, Mark S. Silverberg, Kerstin Lindblad, Hillary Steinhart, Zane Cohen, Terrye Delmonte, Kerry Kocher, Katie Miller, Sheila Guschwan, Edward J. Kulbokas, Sinead O'Leary, Ellen Winchester, Ken Dewar, Todd Green, Valerie Stone, Christine Chow, Albert Cohen, Diane Langelier, Gilles Lapointe, Daniel Gaudet, Janet Faith, Nancy Branco, Shelley B. Bull, Robin S. McLeod, Anne M. Griffiths, Alain Bitton, Gordon R. Greenberg, Eric S. Lander, Katherine A. Siminovitch
& Thomas J. Hudson doi:10.1038/ng1001-223 Abstract|Full text|PDF
(199K)
|Supplementary Information See also:News and Views by Goldstein
High-resolution haplotype structure in the human genomepp229 - 232 Mark J. Daly, John D. Rioux, Stephen F. Schaffner, Thomas J. Hudson
& Eric S. Lander doi:10.1038/ng1001-229 Abstract|Full text|PDF
(117K)
Haplotype tagging for the identification of common disease genespp233 - 237 Gillian C.L. Johnson, Laura Esposito, Bryan J. Barratt, Annabel N. Smith, Joanne Heward, Gianfranco Di Genova, Hironori Ueda, Heather J. Cordell, Iain A. Eaves, Frank Dudbridge, Rebecca C.J. Twells, Felicity Payne, Wil Hughes, Sarah Nutland, Helen Stevens, Phillipa Carr, Eva Tuomilehto-Wolf, Jaakko Tuomilehto, Stephen C.L. Gough, David G. Clayton
& John A. Todd doi:10.1038/ng1001-233 Abstract|Full text|PDF
(189K)
|Supplementary Information See also:News and Views by Goldstein
signaling in tumor suppression and cancer progression
