High-efficiency deleter mice show that FLPe is an alternative to Cre-loxPpp139 - 140 Carolyn I. Rodríguez, Frank Buchholz, Jenna Galloway, Reynaldo Sequerra, Jocelyn Kasper, Ramses Ayala, A. Francis Stewart
& Susan M. Dymecki doi:10.1038/75973 Full text|PDF
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Mutations in SPINK5, encoding a serine protease inhibitor, cause
Netherton syndromepp141 - 142 Stéphane Chavanas, Christine Bodemer, Ariane Rochat, Dominique Hamel-Teillac, Mohsin Ali, Alan D. Irvine, Jean-Louis Bonafé, John Wilkinson, Alain Taïeb, Yann Barrandon, John I. Harper, Yves de Prost
& Alain Hovnanian doi:10.1038/75977 Abstract|Full text|PDF
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Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutationspp143 - 144 Terry Watnick, Ning He, Kairong Wang, Yan Liang, Patrick Parfrey, Donna Hefferton, Peter St George-Hyslop, Gregory Germino
& York Pei doi:10.1038/75981 Abstract|Full text|PDF
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Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogenepp144 - 146 Donna G. Albertson, Bauke Ylstra, Richard Segraves, Colin Collins, Shanaz H. Dairkee, David Kowbel, Wen-Lin Kuo, Joe W. Gray
& Daniel Pinkel doi:10.1038/75985 Abstract|Full text|PDF
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Computer-based three-dimensional visualization of developmental gene expressionpp147 - 152 Johannes Streicher, Markus A. Donat, Bernhard Strauss, Ralf Spörle, Klaus Schughart
& Gerd B. Müller doi:10.1038/75989 Abstract|Full text|PDF
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Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
pp153 - 159 Marika J. Karkkainen, Robert E. Ferrell, Elizabeth C. Lawrence, Mark A. Kimak, Kara L. Levinson, Michele A. McTigue, Kari Alitalo
& David N. Finegold doi:10.1038/75997 Abstract|Full text|PDF
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Identification of the familial cylindromatosis tumour-suppressor genepp160 - 165 Graham R. Bignell, William Warren, Sheila Seal, Meiko Takahashi, Elizabeth Rapley, Rita Barfoot, Helen Green, Carolanne Brown, Patrick J. Biggs, Sunil R. Lakhani, Christopher Jones, Juliana Hansen, Edward Blair, Benedikt Hofmann, Reiner Siebert, Gwen Turner, D. Gareth Evans, Connie Schrander-Stumpel, Frits A. Beemer, Ans van den Ouweland, Dicky Halley, Bertrand Delpech, Mark G. Cleveland, Irene Leigh, Jaakko Leisti, Sonja Rasmussen, Margaret R. Wallace, Christiane Fenske, Piu Banerjee, Naoki Oiso, Ranbir Chaggar, Samantha Merrett, Niamh Leonard, Marcel Huber, Daniel Hohl, Pam Chapman, John Burn, Sally Swift, Anna Smith, Alan Ashworth
& Michael R. Stratton doi:10.1038/76006 Abstract|Full text|PDF
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Plzf regulates limb and axial skeletal patterningpp166 - 172 Maria Barna, Nicola Hawe, Lee Niswander
& Pier Paolo Pandolfi doi:10.1038/76014 Abstract|Full text|PDF
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Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndromepp173 - 176 Gaël Ménasché, Elodie Pastural, Jérôme Feldmann, Stéphanie Certain, Fügen Ersoy, Sophie Dupuis, Nico Wulffraat, Diana Bianchi, Alain Fischer, Françoise Le Deist
& Geneviève de Saint Basile doi:10.1038/76024 Abstract|Full text|PDF
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Features of systemic lupus erythematosus in Dnase1-deficient micepp177 - 181 Markus Napirei, Holger Karsunky, Branko Zevnik, Harald Stephan, Hans Georg M
& Tarik Möröy doi:10.1038/76032 Abstract|Full text|PDF
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Mutations in LHX3 result in a new syndrome revealed by combined pituitary hormone deficiencypp182 - 186 Irène Netchine, Marie-Laure Sobrier, Heiko Krude, Dirk Schnabel, Mohamed Maghnie, Elisabeth Marcos, Bénédicte Duriez, Valère Cacheux, Arpard v. Moers, Michel Goossens, Annette Grüters
& Serge Amselem doi:10.1038/76041 Abstract|Full text|PDF
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TLR4 mutations are associated with endotoxin hyporesponsiveness in humanspp187 - 191 Nancy C. Arbour, Eva Lorenz, Brian C. Schutte, Joseph Zabner, Joel N. Kline, Michael Jones, Kathy Frees, Janet L. Watt
& David A. Schwartz doi:10.1038/76048 Abstract|Full text|PDF
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Homologous recombination is responsible for cell death in the absence
of the Sgs1 and Srs2 helicasespp192 - 194 Serge Gangloff, Christine Soustelle
& Francis Fabre doi:10.1038/76055 Abstract|Full text|PDF
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Mice deficient for - and -opioid receptors exhibit opposing
alterations of emotional responsespp195 - 200 Dominique Filliol, Sandy Ghozland, Johanna Chluba, Miguel Martin, Hans W.D. Matthes, Frédéric Simonin, Katia Befort, Claire Gavériaux-Ruff, Andrée Dierich, Marianne LeMeur, Olga Valverde, Rafael Maldonado
& Brigitte L. Kieffer doi:10.1038/76061 Abstract|Full text|PDF
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More than 1,000 putative new human signalling proteins revealed by EST
data miningpp201 - 204 Jörg Schultz, Tobias Doerks, Chris P. Ponting, Richard R. Copley
& Peer Bork doi:10.1038/76069 Abstract|Full text|PDF
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Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determinationpp205 - 208 Karen W. Gripp, David Wotton, Michael C. Edwards, Erich Roessler, Lesley Ades, Peter Meinecke, Antonio Richieri-Costa, Elaine H. Zackai, Joan Massagué, Maximilian Muenke
& Stephen J. Elledge doi:10.1038/76074 Abstract|Full text|PDF
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Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous systempp209 - 212 Kim-Chew Lim, Ganesh Lakshmanan, Susan E. Crawford, Yi Gu, Frank Grosveld
& James Douglas Engel doi:10.1038/76080 Abstract|Full text|PDF
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Mutations in the gene encoding the serine protease inhibitor, Kazal type
1 are associated with chronic pancreatitispp213 - 216 Heiko Witt, Werner Luck, Hans Christian Hennies, Martin Claen, Andreas Kage, Ulrich La, Olfert Landt
& Michael Becker doi:10.1038/76088 Abstract|Full text|PDF
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Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequencespp217 - 222 Antonia Follenzi, Laurie E. Ailles, Silvia Bakovic, Massimo Geuna
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Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticumpp223 - 227 Olivier Le Saux, Zsolt Urban, Cordula Tschuch, Katalin Csiszar, Barbara Bacchelli, Daniela Quaglino, Ivonne Pasquali-Ronchetti, F. Michael Pope, Allan Richards, Sharon Terry, Lionel Bercovitch, Anne de Paepe
& Charles D. Boyd doi:10.1038/76102 Abstract|Full text|PDF
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Mutations in ABCC6 cause pseudoxanthoma elasticumpp228 - 231 Arthur A.B. Bergen, Astrid S. Plomp, Ellen J. Schuurman, Sharon Terry, Martijn Breuning, Hans Dauwerse, Jaap Swart, Marcel Kool, Simone van Soest, Frank Baas, Jacoline B. ten Brink
& Paulus T.V.M. de Jong doi:10.1038/76109 Abstract|Full text|PDF
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Estimate of human gene number provided by genome-wide analysis using
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& Jean Weissenbach doi:10.1038/76118 Abstract|Full text|PDF
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De novo deletions of SNRPN exon 1 in early human and mouse embryos result in a paternal to maternal imprint switchp241 doi:10.1038/76128 Full text|PDF
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- and 
-opioid receptors exhibit opposing
alterations of emotional responses
en, Andreas Kage, Ulrich La
