Haemochromatosis HFE and genetic complexitypp375 - 376 Neil Risch doi:10.1038/ng1297-375 References|PDF
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Cytosine methylation targetted to pre-determined sequencespp376 - 378 Guo-Liang Xu
& Timothy H. Bestor doi:10.1038/ng1297-376 References|PDF
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Normal meiotic recombination in p53-deficient micepp378 - 379 Kevin M. Gersten
& Christopher J. Kemp doi:10.1038/ng1297-378 References|PDF
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Mouse loci for malaria-induced mortality and the control of parasitaemiapp380 - 381 Simon J. Foote, Rachel A. Burt, Tracey M. Baldwin, Asaf Presente, Andrew W Roberts, Yvette L. Laural, Andrew M. Lew
& Vikki M. Marshall doi:10.1038/ng1297-380 References|PDF
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Genetic control of blood parasitaemia in mouse malaria maps to chromosome 8pp382 - 383 Anny Fortin, Abdelmajid Belouchi, Mi Fong Tam, Lon Cardon, Emil Skamene, Mary M. Stevenson
& Philippe Gros doi:10.1038/ng1297-382 References|PDF
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Mutation in hepatocyte nuclear factor−1 gene (TCF2) associated with MODYpp384 - 385 Yukio Horikawa, Naoko Iwasaki, Manami Hara, Hiroto Furuta, Yoshinori Hinokio, Brian N. Cockburn, Tom Lindner, Kazuya Yamagata, Makiko Ogata, Osamu Tomonaga, Hiroyuki Kuroki, Tadasu Kasahara, Yasuhiko Iwamoto
& Graeme I. Bell doi:10.1038/ng1297-384 References|PDF
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A CAG/CTG expansion in the normal populationpp385 - 386 Mika Nakamoto, Hirohide Takebayashi, Yoshiya Kawaguchi, Shuh Narumiya, Masafumi Taniwaki, Yusuke Nakamura, Yasuhiro Ishikawa, Ichiro Akiguchi, Jun Kimura
& Akira Kakizuka doi:10.1038/ng1297-385 References|PDF
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Positional cloning of the APECED genepp393 - 398 Kentaro Nagamine, Pärt Peterson, Hamish S. Scott, Jun Kudoh, Shinsei Minoshima, Maarit Heino, Kai J. E. Krohn, Maria D. Lalioti, Primus E. Mullis, Stylianos E. Antonarakis, Kazuhiko Kawasaki, Shuichi Asakawa, Fumiaki Ito
& Nobuyoshi Shimizu doi:10.1038/ng1297-393 Abstract + references|PDF
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An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domainspp399 - 403 Johanna Aaltonen, Petra Björses, Jaakko Perheentupa, Nina Horelli−Kuitunen, Aarno Palotie, Leena Peltonen, Yeon Su Lee, Fiona Francis, Steffen Henning, Cora Thiel, Hans Leharach
& Marie−Laure Yaspo doi:10.1038/ng1297-399 Abstract + references|PDF
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Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansionpp404 - 410 Jacqueline K. White, Wojtek Auerbach, Mabel P. Duyao, Jean-Paul Vonsattel, James F Gusella, Alexandra L. Joyner
& Marcy E. MacDonald doi:10.1038/ng1297-404 Abstract + references|PDF
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Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS)pp411 - 422 Lorraine A. Everett, Benjamin Glaser, John C. Beck, Jacquelyn R. Idol, Andreas Buchs, Ma'ayan Heyman, Faiad Adawi, Elizur Hazani, Elias Nassir, Andreas D. Baxevanis, Val C. Sheffield
& Eric D. Green doi:10.1038/ng1297-411 Abstract + references|PDF
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Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutationpp423 - 430 Frances Connor, David Bertwistle, P. Joseph Mee, Gillian M. Ross, Sally Swift, Elena Grigorieva, Victor L. J. Tybulewicz
& Alan Ashworth doi:10.1038/ng1297-423 Abstract + references|PDF
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Rapid accumulation of genome rearrangements in liver but not in brain of old micepp431 - 434 Martijn E.T. Dollé, Heidi Giese, Craig L. Hopkins, Hans-Jörg Martus, Jeffrey M. Hausdorff
& Jan Vijg doi:10.1038/ng1297-431 Abstract + references|PDF
(436K)
Demographic history and linkage disequilibrium in human populationspp435 - 438 Maris Laan
& Svante Pääbo doi:10.1038/ng1297-435 Abstract + references|PDF
(310K)
Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formationpp439 - 444 Peter Carmeliet, Lieve Moons, Roger Lijnen, Myriam Baes, Vincent Lemaître, Peter Tipping, Angela Drew, Yves Eeckhout, Steve Shapiro, Florea Lupu
& Désiré Collen doi:10.1038/ng1297-439 Abstract + references|PDF
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Mutations in PEX1 are the most common cause of peroxisome biogenesis disorderspp445 - 448 Bernadette E. Reuber, Emily Germain-Lee, Cynthia S. Collins, James C. Morrell, Rohan Ameritunga, Hugo W. Moser, David Valle
& Stephen J. Gould doi:10.1038/ng1297-445 Abstract + references|PDF
(566K)
Human PEX1 is mutated in complementation group 1 of the peroxisome biogenesis disorderspp449 - 452 Herma Portsteffen, Andreas Beyer, Elisabeth Becker, Cornelia Epplen, André Pawlak, Wolf-H Kunau
& Gabriele Dodt doi:10.1038/ng1297-449 Abstract + references|PDF
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Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathwayspp453 - 456 Carrolee Barlow, Kevin D. Brown, Chu-Xia Deng, Danilo A. Tagle
& Anthony Wynshaw-Boris doi:10.1038/ng1297-453 Abstract + references|PDF
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ATM and RPA in meiotic chromosome synapsis and recombinationpp457 - 461 Annemieke W. Plug, Antoine H.F.M Peters, Yang Xu, Kathleen S. Keegan, Merl F. Hoekstra, David Baltimore, Peter de Boer
& Terry Ashley doi:10.1038/ng1297-457 Abstract + references|PDF
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Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null allelespp462 - 466 Carrolee Barlow, Marek Liyanage, Peter B. Moens, Chu-Xia Deng, Thomas Ried
& Anthony Wynshaw-Boris doi:10.1038/ng1297-462 Abstract + references|PDF
(871K)
Donor splice-site mutations in WT1 are responsible for Frasier syndromepp467 - 470 Sandrine Barbaux, Patrick Niaudet, Marie-Claire Gubler, Jean-Pierre Grünfeld, Francis Jaubert, Frédérique Kuttenn, Claire Nihoul Fékété, Nicole Souleyreau-Therville, Elisabeth Thibaud, Marc Fellous
& Ken McElreavey doi:10.1038/ng1297-467 Abstract + references|PDF
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Genetic analysis of ozone-induced acute lung injury in sensitive and resistant strains of micepp471 - 474 Daniel R. Prows, Howard G. Shertzer, Mark J. Daly, Charles L. Sidman
& George D. Leikauf doi:10.1038/ng1297-471 Abstract + references|PDF
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Linkage analysis of susceptibility to ozone-induced lung inflammation in inbred micepp475 - 478 Steven R. Kleeberger, Roy C. Levitt, Liu-Yi Zhang, Malinda Longphre, Jack Harkema, Anne Jedlicka, Scott M. Eleff, Deborah DiSilvestre
& Kenneth J. Holroyd doi:10.1038/ng1297-475 Abstract + references|PDF
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Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesispp479 - 482 Ciaran Morrison, Graeme C.M. Smith, Laura Stingl, Stephen P. Jackson, Erwin F. Wagner
& Zhao-Qi Wang doi:10.1038/ng1297-479 Abstract + references|PDF
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DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locuspp483 - 486 Chamelli Jhappan, Herbert C. Morse III, Robert D. Fleischmann, Michael M. Gottesman
& Glenn Merlino doi:10.1038/ng1297-483 Abstract + references|PDF
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The Fanconi anaemia proteins, FAA and FAC interact to form a nuclear complexpp487 - 490 Gary M. Kupfer, Dieter Näf, Ahmed Suliman, Michael Pulsipher
& Alan D. D'Andrea doi:10.1038/ng1297-487 Abstract + references|PDF
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Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndromepp491 - 494 Colin T. Dolphin, Azara Janmohamed, Robert L. Smith, Elizabeth A. Shephard
& lan R. Phillips doi:10.1038/ng1297-491 Abstract + references|PDF
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EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenicpp495 - 497 William A. May, Afsane Arvand, Andrew D. Thompson, Benjamin S. Braun, Marcienne Wright
& Christopher T. Denny doi:10.1038/ng1297-495 Abstract + references|PDF
(403K)
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRTpp498 - 502 Scott L. Weinrich, Ron Pruzan, Libin Ma, Michel Ouellette, Valeric M. Tesmer, Shawn E. Holt, Andrea G. Bodnar, Serge Lichtsteiner, Nam W. Kim, James B. Trager, Rebecca D. Taylor, Ruben Carlos, William H. Andrews, Woodring E. Wright, Jerry W. Shay, Calvin B. Harley
& Gregg B. Morin doi:10.1038/ng1297-498 Abstract + references|PDF
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gene (TCF2) associated with MODY
