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Published online 12 May 2009 | Nature | doi:10.1038/459146b
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Exome sequencing takes centre stage in cancer profiling
Researchers question focus on coding regions.
COLD SPRING HARBOR
To help battle their way through the stream of data coming in from human gene sequencing, major cancer-genome screening projects such as the International Cancer Genome Consortium (ICGC) seem to be choosing to simplify matters.
The ICGC aims eventually to sequence the full genomes of 25,000 tumour samples as well as those of the people from whom the tumours were taken, which would give 50,000 distinct genomes.
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