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Published online 15 July 2003 | Nature | doi:10.1038/news030714-3

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Frog eggs rejuvenate human cells

Amphibian extract may take adult DNA back to stem-cell state.

Immature frog eggs can rejuvenate adult human cells. Molecules in the amphibian nucleus coax mature human and mouse DNA back to an adaptable, stem-cell-like state1.

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