First rat to have key genes altered.
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References
Zan, Y. et al. Production of knockout rats using ENU mutagenesis and a yeast-based screening assay. Nature Biotechnology, published online, doi:10.1038/nbt830 (2003).
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Pilcher, H. It's a knockout. Nature (2003). https://doi.org/10.1038/news030512-17
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DOI: https://doi.org/10.1038/news030512-17