Nature Neuroscience 9, 857 - 859 (2006)
doi:10.1038/nn0706-857
Fool me once, shame on me—fool me twice, blame the ACCBenjamin Y Hayden
& Michael L Platt
The authors are in the Department of Neurobiology, Center for Neuroeconomic Studies, and Center for Cognitive Neuroscience, Duke University Medical Center, Durham, North Carolina 27710, USA. platt@neuro.duke.edu
The anterior cingulate cortex (ACC) is thought to detect unfavorable outcomes and thus influence behavior. A new paper reports that ACC-lesioned monkeys respond normally to reduced rewards, but do not maintain their improved behavioral strategy. The ACC thus is not a simple error detector, but an integrator of past reward experience.
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