 | Figure 1
Nature Neuroscience
8, 697 - 699 (2005)
doi:10.1038/nn0605-697
A woman's prerogativeKevin Staley
& Helen Scharfman | | | | Figure 1. Comparison of the estrous cycle of the rat and menstrual cycle of the human.
(a) The 4-day estrous cycle of the rat (gray bars indicate night, 6 p.m. to 6 a.m.), showing fluctuations in estrogen, progesterone, luteinizing hormone (LH) and follicle-stimulating hormone (FSH). The arrow indicates the approximate time of progesterone withdrawal and potential change in  subunit expression suggested by the findings of Maguire et al. In the mouse, the estrous cycle is similar, but varies in length (4−7 days) and is less well defined. (b) The human 28-day menstrual cycle. The time of progesterone withdrawal is thought to be at the end of the cycle, approximately at the onset of menses. Seizure susceptibility increases at this time, but in some individuals seizure susceptiblity may also increase at the time of ovulation, or during anovulatory cycles10. Adapted from ref. 15.
Ann Thomson |
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