Nature Neuroscience
8, 458 - 467 (2005)
Published online: 6 March 2005; | doi:10.1038/nn1416
LAR receptor protein tyrosine phosphatases in the development and maintenance of excitatory synapsesAnthone W Dunah, Emily Hueske, Michael Wyszynski, Casper C Hoogenraad, Jacek Jaworski, Daniel T Pak, Alyson Simonetta, Guosong Liu
& Morgan ShengSupplementary Fig. 1 (pdf 305K) Expression of endogenous LAR-RPTP in cultured hippocampal neurons. Supplementary Fig. 2 (pdf 715K) LAR interfering constructs reduce dendritic spine density in immature hippocampal neurons. Supplementary Fig. 3 (pdf 322K) Overexpression of LAR mutants disrupts surface expression of AMPA receptors and dendritic targeting of -catenin and cadherin. Supplementary Fig. 4 (pdf 403K) Overexpression of wildtype LAR inhibits the effect of dominant negative LAR mutants on surface AMPA receptors and PSD-95 density. Supplementary Fig. 5 (pdf 157K) Efficacy and specificity of LAR-RPTP RNAi constructs. Supplementary Methods (pdf 20K)
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